They are finally realizing that anything promoting blood vessel inflammation, in this case excess niacin metabolites, can lead to cardiovascular disease. It's not the cholesterol.
https://consultqd.clevelandclinic.org/link-discovered-between-excess-niacin-and-cardiovascular-disease
Phase I, pilot study in healthy volunteers, to assess the safety and pharmacokinetics of PCO-02, which active ingredient is BPC-157, a pentadecapeptide from gastric source.
Conducted in 2015.
Canceled in 2016 with NO EXPLANATION - either not effective or dangerous...
If you have the typical digestive symptoms (nausea, belching, acid reflex etc) or other vague unexplained symptoms (fatigue, depression, low immune system) that may be related to H. Pylori, it is a good idea to test. About 50% of the population are infected but many are asymptomatic carriers...
Japanese review of the amazing health benefits of this particular probiotic strain:
https://www.sciencedirect.com/science/article/pii/S1756464619300684#b0240
This particular strain of Bifidobacterium can be found in many of the "pearls" of Nature's Way. The pearls have a triple layer...
I just processed a refund on Amazon.com by chatting online to an Artificial Intelligence instead of the usual human agent. Its replies were coming out in the characteristic spastic manner of ChatGPT. I asked and it confirmed that it was Artificial Intelligence. It ignored and didn't answer my...
Keep in mind that this review article does not differentiate between Ejaculation and Orgasm. Some of the proposed drugs stimulate Ejaculation, not Orgasm: ephedra extracts/teas, ephedrine, pseudo-ephedrine. They can cause premature ejaculation without pleasure (orgasm) because they contract some...
This is for the people that want to increase their HDL.
I am not on TRT and my usual HDL is around 60 mg/dL.
About 1.5months ago, I started a diet with a high cheese consumption: 8 oz cheese daily = about 900 calories, out of about 2000 total daily calories (my diet is mainly cheese, rice...
The doses used were high to common standards:
100mg/kg Glycine per day
100mg/kg NAC per day
a 70kg (154lb) human would have to take 7g Glycine and 7g NAC per day
GlyNAC (Glycine and N-Acetylcysteine) Supplementation Improves Impaired Mitochondrial Fuel Oxidation and Lowers Insulin Resistance...
The doses were a bit high:
1.33 mmol/kg/d of glycine = 100mg/kg per day
0.81 mmol/kg/d of cysteine (as N-acetylcysteine) = 100mg/kg per day
a 70kg person (154lb) would have to take 7g Glycine and 7g NAC per day.
Effect of Increasing Glutathione With Cysteine and Glycine Supplementation on...
GlyNAC (Glycine and N-Acetylcysteine) Supplementation in Mice Increases Length of Life by Correcting Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Abnormalities in Mitophagy and Nutrient Sensing, and Genomic Damage
Supplementing Glycine and N-Acetylcysteine (GlyNAC) in...
A very instructive article on the evolution of the fish oil health claims (it's now a drug), which illustrates the contemporary quackery in the supplement industry:
Fish Oil Is Good! No, Bad! No, Good! No, Wait
I take Andrographis when I need an immunity boost, but I noticed on several occasions already that in a few hours after I take it, I experience a sudden interest in sex. I am a 49yo male and feel horny extremely RARELY.
Andrographis seems to dilate the varicose veins in my legs (they start...
What sugar substitute do you use and for what: drinks, pudding, cake, cookies etc?
To limit my sugar consumption, I use sucralose in a cup of hot cocoa, cocoa rice pudding with rice flower, or sometimes to sweeten protein shakes.
Sucralose works ok for that and you need very little amount...
Has anyone tried bromantane? Supposedly it is an "atypical stimulant" that "doesn't cause over-stimulation". What was your dose, for long you took it, and what was your experience?
The Russian research on it reads like typical fairy-tales. It's so great supposedly, that they stopped producing...
The idea behind sublingual/intranasal testosterone is that it is absorbed fast and decreases fast. Expect increases in DHT since it passes through mucous membranes.
Natesto is a nasal spray that contains 0.0055g testosterone/ 0.122g gel = 4.5% gel. The solvents used are castor oil and oleoyl...
I just got a trans-dermal (micronized) progesterone cream to try it to help me fall asleep at night.
I am interested to hear male experiences about it, with or without TRT. How did it affect your sleep, libido, erection, orgasm, and testosterone levels if you measured those?
The purported...
Could pineapples be a new weapon against COVID-19:
The Bromelain concentration tested was 75 micrograms/mL which might be achievable by supplementation. Still, this is only in vitro study in monkey kidney cells. It is not clear if the necessary concentration can be achieved in human lungs and...
The study shows a correlation: countries with a high vaccination rate of MMR vaccine show a lower COVID-19 death rate per 100 000 population. However, correlation studies are not capable of pinpointing the exact cause of reduced mortatlity - is it the MMR vaccine itself or something else that...
I am a 46 yo male, skinny-flabby, HIV positive (undetectable but with immune system that is still not recovered). I go to gym 4-5 days a week but often don't have the energy to finish the workout, muscles remain lame, strength does not increase, have no energy during the day and some fat in face...
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