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    Excess niacin causes blood vessel inflammation and cardiovascular disease

    They are finally realizing that anything promoting blood vessel inflammation, in this case excess niacin metabolites, can lead to cardiovascular disease. It's not the cholesterol. https://consultqd.clevelandclinic.org/link-discovered-between-excess-niacin-and-cardiovascular-disease
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    A human trial of oral BPC-157 was quickly canceled

    Phase I, pilot study in healthy volunteers, to assess the safety and pharmacokinetics of PCO-02, which active ingredient is BPC-157, a pentadecapeptide from gastric source. Conducted in 2015. Canceled in 2016 with NO EXPLANATION - either not effective or dangerous...
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    Liposomal Lactoferrin as antiviral treatment in mild to moderate Covid-19

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8535893/
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    Little known effects of H. Pylori infection on health

    If you have the typical digestive symptoms (nausea, belching, acid reflex etc) or other vague unexplained symptoms (fatigue, depression, low immune system) that may be related to H. Pylori, it is a good idea to test. About 50% of the population are infected but many are asymptomatic carriers...
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    The probiotic Bifidobacterium Longum BB536 reduces constipation/diarrhea, normalizes the gut microbiome, increases immunity, and suppresses allergies

    Japanese review of the amazing health benefits of this particular probiotic strain: https://www.sciencedirect.com/science/article/pii/S1756464619300684#b0240 This particular strain of Bifidobacterium can be found in many of the "pearls" of Nature's Way. The pearls have a triple layer...
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    AI is already replacing Amazon workers

    I just processed a refund on Amazon.com by chatting online to an Artificial Intelligence instead of the usual human agent. Its replies were coming out in the characteristic spastic manner of ChatGPT. I asked and it confirmed that it was Artificial Intelligence. It ignored and didn't answer my...
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    Arthritis drug rejuvenates blood stem cells in mice

    https://newatlas.com/medical/arthritis-drug-young-blood-reverses-aging-mice/
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    Melatonin can enhance immunity in older or ill people and possibly prolong life

    https://immunityageing.biomedcentral.com/articles/10.1186/1742-4933-2-17
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    Frequent viagra use correlates with a reduced risk of heart attack in men with cardiovascular disease

    https://www.healthline.com/health-news/viagra-may-help-men-with-coronary-artery-disease-live-longer
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    Drugs that MIGHT work for Delayed Ejaculation OR Delayed Orgasm (low penis sensitivity after erection)

    Keep in mind that this review article does not differentiate between Ejaculation and Orgasm. Some of the proposed drugs stimulate Ejaculation, not Orgasm: ephedra extracts/teas, ephedrine, pseudo-ephedrine. They can cause premature ejaculation without pleasure (orgasm) because they contract some...
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    Another score for meat-only (carnivore) diet against deranged autoimmunity

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    Long Covid: Covid found in brain long after infection

    https://scitechdaily.com/covid-19-virus-found-in-the-brain-autopsies-reveal-startling-new-information/#comment-734741
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    Recent knowledge that human body contains mostly ... viruses

    https://www.scientificamerican.com/article/viruses-can-help-us-as-well-as-harm-us/
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    Two very common latent viruses Varicella Zoster and Herpes 1 may trigger Alzheimer

    https://www.medicalnewstoday.com/articles/how-varicella-and-herpes-viruses-may-interact-to-trigger-alzheimers#A-new-way-to-prevent-Alzheimers?
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    High cheese consumption boosted my HDL

    This is for the people that want to increase their HDL. I am not on TRT and my usual HDL is around 60 mg/dL. About 1.5months ago, I started a diet with a high cheese consumption: 8 oz cheese daily = about 900 calories, out of about 2000 total daily calories (my diet is mainly cheese, rice...
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    High doses Glycine + NAC for 2 weeks mproved Impaired Mitochondrial Fuel Oxidation and Lowers Insulin Resistance in Patients with Type 2 Diabetes

    The doses used were high to common standards: 100mg/kg Glycine per day 100mg/kg NAC per day a 70kg (154lb) human would have to take 7g Glycine and 7g NAC per day GlyNAC (Glycine and N-Acetylcysteine) Supplementation Improves Impaired Mitochondrial Fuel Oxidation and Lowers Insulin Resistance...
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    High doses Glycine + NAC supplementation improved body composition, health markers and aging in Older HIV patients

    The doses were a bit high: 1.33 mmol/kg/d of glycine = 100mg/kg per day 0.81 mmol/kg/d of cysteine (as N-acetylcysteine) = 100mg/kg per day a 70kg person (154lb) would have to take 7g Glycine and 7g NAC per day. Effect of Increasing Glutathione With Cysteine and Glycine Supplementation on...
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    Glycine and NAC supplementation increased mice lifespan by 24% and improved health in older adults

    GlyNAC (Glycine and N-Acetylcysteine) Supplementation in Mice Increases Length of Life by Correcting Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Abnormalities in Mitophagy and Nutrient Sensing, and Genomic Damage Supplementing Glycine and N-Acetylcysteine (GlyNAC) in...
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    Hilarious pic

    I found this hilarious: Top Scientist Admits Webb Telescope Star Photo Was Actually Chorizo
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    Fish Oil Hype

    A very instructive article on the evolution of the fish oil health claims (it's now a drug), which illustrates the contemporary quackery in the supplement industry: Fish Oil Is Good! No, Bad! No, Good! No, Wait
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    Andrographis is a libido booster for me

    I take Andrographis when I need an immunity boost, but I noticed on several occasions already that in a few hours after I take it, I experience a sudden interest in sex. I am a 49yo male and feel horny extremely RARELY. Andrographis seems to dilate the varicose veins in my legs (they start...
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    What sugar substitute do you use?

    What sugar substitute do you use and for what: drinks, pudding, cake, cookies etc? To limit my sugar consumption, I use sucralose in a cup of hot cocoa, cocoa rice pudding with rice flower, or sometimes to sweeten protein shakes. Sucralose works ok for that and you need very little amount...
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    Bromantane experiences ?

    Has anyone tried bromantane? Supposedly it is an "atypical stimulant" that "doesn't cause over-stimulation". What was your dose, for long you took it, and what was your experience? The Russian research on it reads like typical fairy-tales. It's so great supposedly, that they stopped producing...
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    Dissolving testosterone for sublingual or intranasal

    The idea behind sublingual/intranasal testosterone is that it is absorbed fast and decreases fast. Expect increases in DHT since it passes through mucous membranes. Natesto is a nasal spray that contains 0.0055g testosterone/ 0.122g gel = 4.5% gel. The solvents used are castor oil and oleoyl...
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    Transdermal progesterone use in men

    I just got a trans-dermal (micronized) progesterone cream to try it to help me fall asleep at night. I am interested to hear male experiences about it, with or without TRT. How did it affect your sleep, libido, erection, orgasm, and testosterone levels if you measured those? The purported...
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    Two New Drugs to Treat COVID-19 from Merck and Pfizer

    New antiviral drug completely suppresses SARS-CoV-2 transmission within 24 hours:
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    Bromelain inhibits COVID-19 in vitro by degrading/cleaving the viral spike protein and two host cell surface receptors

    Could pineapples be a new weapon against COVID-19: The Bromelain concentration tested was 75 micrograms/mL which might be achievable by supplementation. Still, this is only in vitro study in monkey kidney cells. It is not clear if the necessary concentration can be achieved in human lungs and...
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    AeroNabs: a promising antiviral nasal spray against COVID-19

    ‘AeroNabs’ Promise Powerful, Inhalable Protection Against COVID-1:
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    Favipiravir: positive effect for mild to moderate cases of COVID-19

    Glenmark’s phase III favipiravir study finds drug speeds clinical improvement for some patients Favipiravir COVID-19 studies summary:
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    MMR vaccine may protect from COVID-19 complications

    The study shows a correlation: countries with a high vaccination rate of MMR vaccine show a lower COVID-19 death rate per 100 000 population. However, correlation studies are not capable of pinpointing the exact cause of reduced mortatlity - is it the MMR vaccine itself or something else that...
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    Oxandrolone with 10mg DHEA at the end: blood tests and my experience

    I am a 46 yo male, skinny-flabby, HIV positive (undetectable but with immune system that is still not recovered). I go to gym 4-5 days a week but often don't have the energy to finish the workout, muscles remain lame, strength does not increase, have no energy during the day and some fat in face...
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