Search results

Defy Medical TRT clinic doctor
  1. Gianluca

    Help me make up my mind about a change in protocol

    I have been using the BD for daily injection for a couple of weeks now. They work great, I used to get a lump after a while on my delt using 29G cheaper brand, not with this brand and G size, worth the extra $!
  2. Gianluca

    NDT Afternoon dose and sleep latency? how do you split your dose?

    Hi guys, For those of you using NDT like Armour or NP, how do you split your dose? What time do you take your PM dose so it doesn’t interfere with your sleep?
  3. Gianluca

    Where to get HCG as of 10/2025

    I paid around $60 for 3 vials of 5000IU
  4. Gianluca

    Where to get HCG as of 10/2025

    yes, mine arrived on Monday of this week, faster then expected
  5. Gianluca

    Where to get HCG as of 10/2025

    I ordered mine 10 days ago, it shipped and it says it will arrive between Nov 16/28
  6. Gianluca

    Where to get HCG as of 10/2025

    I don’t know
  7. Gianluca

    Where to get HCG as of 10/2025

    I called, it is all good Thanks For some reason I had to call them this time to have the payment method link sent. Good think you guys told me otherwise I would have assumed by their email shipping was not available to the US
  8. Gianluca

    Where to get HCG as of 10/2025

    I just realized ReliableRX is not currently shipping to the US, where are you guys sourcing the HCG as of right now?
  9. Gianluca

    Help me make up my mind about a change in protocol

    just got my BD. @Gman86 this is a quick research with AI BD vs Easy touch, it seems for daily microdosing BD is worth: BD Needles are micro-polished and triple-beveled; users often describe them as “noticeably sharper” and smoother to insert — particularly for subcutaneous or shallow IM...
  10. Gianluca

    Help me make up my mind about a change in protocol

    I was thinking about this. I use Test E in sesame oil, which I believe is one of the most viscous oils. I also did some research on how different muscles may disperse the oil at different rates. For example, the vastus lateralis may release the oil more gradually. So, combining a viscous oil...
  11. Gianluca

    Help me make up my mind about a change in protocol

    on 18mg daily subQ my FT is around 13.8 and daily IM about 22 and feel the difference. Once I tried 30mg SubQ daily, and the only increase I saw was in HCT, my FT only at 20. I think I'll stick with ED IM for now. thanks for your input here.
  12. Gianluca

    Help me make up my mind about a change in protocol

    Hi guys, After trying subQ injection for my 3rd time with no success, I think I'm left to go back to IM injections. I just don't absorb subQ as well as IM. I'm debating if I should go back again to either EOD or ED as injection frequency. I would choose ED as a peace of mind about having...
  13. Gianluca

    Elevated Hematocrit from Testosterone Therapy vs High-Altitude Adaptation: A Comparative Analysis

    thank you for posting this well written article.
  14. Gianluca

    Timeline of Testosterone Research & Measurement

    I was using AI for some research, it made an interesting quick summary of Testosterone. I thought I would share. Pre-1935 – Theories of male virility Ancient and early medical theories linked testes with masculinity. Castration known to affect physical and behavioral traits. No chemical...
  15. Gianluca

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    Lucky!
  16. Gianluca

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    You are lucky. Are you injecting SubQ or IM? If subQ, what injection site(s) do you use?
  17. Gianluca

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    I have not, thanks for bringing this up. Since injecting everyday, I generally get the blood draw about 2hrs post injection, but sometime I believe I went prior injection, and levels come back about the same. However, I have gone in the past in the late afternoon, and TT seems to come back...
  18. Gianluca

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    it is still hard to believe to me my body is able to clear that fast testosterone even if I inject it daily, but I understand now that this can be the main reason why my levels are not above range with this dose. Unless at the cellular level things look different.
  19. Gianluca

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    I just calculated again my FT with Tru calculator, and my FT is 18.64ng/dl, direct method is 19.4 pg/ml
  20. Gianluca

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    throughout the years I used mostly the direct method. However, since the discussions in here, a couple years ago I started to use the Equilibrium ultrafiltration from LabCorp, and FT levels came back about the same as direct method. I also calculated FT with the Tru calculator, and FT matched...
  21. Gianluca

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    Considering the daily natural production of a healthy young male, you would think that if someone inject 100mg tot weekly either using a daily or EOD protocol with an ester like Cypionate, we would see both TT and FT above range, theoretically. However, people like me: for example I inject...
  22. Gianluca

    Regular testosterone test overestimates hypogonadism in men compared to the LC-MS/MS assay

    it makes sense, especially with primary hypo. Perhaps then just like Thyroid and TSH, fully suppressing LH may mean we are taking in too much Test, or too much in one dose.
  23. Gianluca

    Regular testosterone test overestimates hypogonadism in men compared to the LC-MS/MS assay

    Doesn’t LH go to 0 regardless of the dose of testosterone used when using an ester like cypionate? I would guess then people daily microdosing with such a ester type don’t have their LH down to 0
  24. Gianluca

    T.Cyp 100 mg/week - Night sweats, anxiety

    @madman Do you believe then that when using TC/TE at once or twice per week injection schedule, is actually more advantageous/normal for the body, vs on a ED schedule when same ester is used since there is going to be a more pronounced peak and valley, even thought that is not lived daily?
  25. Gianluca

    DSIP Spray

    I was doing some research with ai, according to anecdotes around the internet, subcutaneous injections seem to give more consistent results than nasal spray. I may try the injection.
  26. Gianluca

    DSIP Spray

    How did it work for you? I'm currently looking at this or the Selank
  27. Gianluca

    T3 and muscle loss

    also, when you running low on T3, the body will secrete more cortisol/adrenaline to compensate, that its self cause muscle loss
  28. Gianluca

    High testosterone is like … finasteride? Say what!

    thanks for sharing!
  29. Gianluca

    High testosterone is like … finasteride? Say what!

    At this point the blend Propionate/CYP or ENA to take daily, may be probably the best physiological option to get test into circulation considering metabolites conversion with some daily fluctuation in T, without letting testosterone dropping too low a couple of times in 24hr like the orals do...
  30. Gianluca

    High testosterone is like … finasteride? Say what!

    @Vince Are you still injecting everyday IM?
  31. Gianluca

    High testosterone is like … finasteride? Say what!

    as far as pharmacokinetics, if I remember correctly, scrotal cream applied once per day only is the closet to mimic endogenous T production. Too bad the DHT issue classify it far away from physiologic to me.
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic doctor
Defy Medical TRT clinic

Sponsors

buy enclomiphene
penile girth enlargement
Discounted Labs
Testosterone Doctor Near Me
Register on ExcelMale.com
Trimix HCG Offer Excelmale
BUY HCG CIALIS
Beyond Testosterone Book by Nelson Vergel

Beyond Testosterone Podcast

Back
Top