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Testosterone Dose and Cardiomyopathy/left ventricular hypertrophy development

Hi Guys, I've read that testosterone doses of more than about 100 mg/week can cause cardiomyopathy and or left ventricular hypertrophy when used long term. On the other hand, renowned experts like Dr. McClain recommend a starting dose of 200 mg for TRT. What is your guys opinion on this? I've...
- Kaus Klinski
- Thread
- Mar 4, 2021
- cardiomyopathy
- Replies: 6
- Forum: Testosterone Side Effect Management
NAC and zinc interaction when taken at the same time

Hi, there is evidence that high dose NAC can cause depletion of zinc when taken long term by forming a complex with the zinc and increasing it's renal excretion (see linked studies below). I wonder, if it is OK to take 600 mg NAC with zinc/ZMA at the same time or if it would compromise the...
- Kaus Klinski
- Thread
- Sep 16, 2019
- nac zinc
- Replies: 1
- Forum: Nutrition and Supplements
MSM and Vitamin C (Ascorbic Acid) Mix - strange smell

Hi, maybe one of you more experienced users can tell me something about this: I mixed 500 g MSM with a small amount of ascorbic acid (hoping to achieve a synergistic effect on collagen synthesis etc.), and the mixture developed a strange, sweetish smell (similar to sugar beet syrup). AFAIK...
- Kaus Klinski
- Thread
- Aug 18, 2019
- msm
- Replies: 0
- Forum: Nutrition and Supplements
ALA and thyroid hormone

Hi guys, I think this topic is worth it to open up a new thread. I decided to add some ALA to my post workout shake (about 250 mgs) to enhance glucose uptake/insulin sensitivity a little. But now I found information that ALA may interfere with thyroid medication (levothyroxine) and I'm on...
- Kaus Klinski
- Thread
- Aug 11, 2019
- alpha lipoic acid
- Replies: 20
- Forum: Nutrition and Supplements
Niacin and lipolysis - does it inhibit/impair fat loss?

Hi, I'm currently thinking about adding some niacin to my supplement stack (about 250-500 mg/day) for it's beneficial effects on the lipid profile, mainly, I'd like to up my HDL a little. But I'm concerned about it's potent antilipolytic effects (which is the actual mechanism behind it's...
- Kaus Klinski
- Thread
- Aug 8, 2019
- niacin
- Replies: 22
- Forum: Nutrition and Supplements

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038