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PSA spike

I am 66 and my PSA has pretty consistantly been around .6 I started TRT injections and while i have been taking a relatively small amount at .25 twice a week, in a little after a month my T went from 260 to over 800, but my PSA has more than doubled. does this happen with TRT?
- stickersteve
- Thread
- Aug 20, 2025
- psa free psa cypionate trt
- Replies: 2
- Forum: Testosterone Side Effect Management
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Pain after subq injections

I have been doing injections for a few weeks now. I started with IM but hit a nerve in my thigh and the doc said I can switch to subq. I am using smaller 25 guage 5/8" syringes for the sub q and I still get pain in the injection area for the next could days after injecting. Thy suggested doing...
- stickersteve
- Thread
- Aug 14, 2025
- subcutaneous injections
- Replies: 5
- Forum: Testosterone Basics & Questions
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Did I hit a nerve?

I just started injecting a couple weeks ago. The first two went great. I did my third on saturday and thought that one also went great but yesterday, two days after the injection I have terrible pain in my thigh. Kept me up most of the night, so I guess I hit a nerve and had a delayed reaction...
- stickersteve
- Thread
- Aug 5, 2025
- injection site reaction
- Replies: 7
- Forum: Testosterone Basics & Questions
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starting injections soon a little nervous

I will be starting T injections next week. I did them many years ago but had one bad experience when I hit a nerve in my thigh and had a hard time walking for a few days so I am a little nervous. I will probably try the thigh again, but I have read that they can also go in the stomach? Is that...
- stickersteve
- Thread
- Jul 12, 2025
- injections
- Replies: 14
- Forum: Testosterone Basics & Questions
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Testosterone anxiety?

I have been on transscrotal testosterone crème for about a month now. All of a sudden my anxiety is as bad as it has ever been. I am not blaming the testosterone, but is it a possibility? If so do all methods of testosterone cause possible anxiety?
- stickersteve
- Thread
- Jun 17, 2025
- anxiety crème
- Replies: 6
- Forum: Testosterone Side Effect Management
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can metformin lower testosterone?

I have been on enclomiphene for the past couple months and my testosterone went from 259 to 224. I was expecting it to raise my level. I thought I saw somewhere that metformin can lower testosterone. does anyone know if that is true?
- stickersteve
- Thread
- May 13, 2025
- enclomiphene citrate metformin
- Replies: 3
- Forum: Testosterone Basics & Questions
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enclomiphone lowered my testosterone

so it looks like enclomiphene was a waste of time for me. I was on 12.5 for about 45 days and my testosterone went from 259 to 224. how can that be. I thought enclomiphene. guess I will go back to troches
- stickersteve
- Thread
- May 12, 2025
- enclomiphene citrate
- Replies: 5
- Forum: hCG, Clomid & Others for Fertility, PCT or Low T
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metformin and libido

I have been taking metformin for about a month, mainly for its health protective potential and to help me lose a little weight. I do not have diabetes. I have lost a few pounds, but I think it may be lowering my libido. I did not know that could be a possible side effect until I read it...
- stickersteve
- Thread
- Dec 15, 2024
- metformin
- Replies: 2
- Forum: Weight Loss Options
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trans scrotal application working

After seeing an earlier post here about trans scrotal application I decided to try it myself. So far it seems to be working. I have been doing it for about two months now. my testosterone went from about 280 to 441. I am 65. while I still dont have morning wood every day, I at least have urges...
- stickersteve
- Thread
- Jan 29, 2024
- testosterone application sites
- Replies: 4
- Forum: Testosterone Basics & Questions
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starting trans scrotal. have questions

I am starting trans scrotal cream as soon as my prescription is filled. I have tried under the tongue troches before which did nothing for me and years ago I tried cream (on the arms) and also my testosterone did not go up. I never heard of this trans scrotal until I came here. I am 64 and not...
- stickersteve
- Thread
- Nov 10, 2023
- scrotal testosterone
- Replies: 6
- Forum: Testosterone Basics & Questions
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Kind of new here would like a little advice

I have been monitoring this site watching everyones posts for years but have never posted, but now I need a little advise. I am 64, have felt like crap for years. I have crohns so that is a major part of it. I have tried testosterone off and on but never stuck with it. Once I tried shots, hit a...
- stickersteve
- Thread
- Jul 20, 2023
- testsosterone
- Replies: 9
- Forum: Testosterone Basics & Questions
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androgel?

I am thinking about starting testosterone therapy again. years ago I tried shots that I gave to myself. It was ok until I injected in the wrong spot one day and felt like I gave myself sciatica so I stopped that. then I tried a cream from a compounding pharmacy. I am very hairy and it was a...
- stickersteve
- Thread
- Jan 19, 2022
- androgel vs injections
- Replies: 1
- Forum: Testosterone Basics & Questions
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felt worse on testosterone

Is it possible to feel worse on testosterone? I started taking a testosterone cream, at a fairly low dose, but seemed to notice an increase in anxiety and brain fog. I had taken testosterone years ago and do not recall this happening. Has anyone ever had adverse effects when starting...
- stickersteve
- Thread
- Jan 22, 2020
- testosterone cream protocol
- Replies: 2
- Forum: Testosterone Basics & Questions
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can testosterone cause anxiety

I have taken testosterone before under the tongue and shots, but stopped them after a while since I did not really feel any better. I just got a cream from a new compounding pharmacy and took it yesterday and today and noticed my anxiety level was as high as it has been in years. I even had to...
- stickersteve
- Thread
- Nov 18, 2019
- testosterone anxiety
- Replies: 22
- Forum: Testosterone Basics & Questions
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thoughts on a gel for me

I have tried testosterone on and off over the years but I never stick with it. I first tried the self injections but a couple times hit a muscle and was sore for a week so I gave up on them. Then I tried the under the tongue trocees (or however you spell it) they took forever to dissolve that...
- stickersteve
- Thread
- Nov 6, 2019
- test gel
- Replies: 6
- Forum: Testosterone Basics & Questions
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testosterone patches

Has anyone tried the patches from Age Force? I just got some and am going to try them for a couple months and see where my level is. I dont like creams because I am to hairy. I dont like giving myself shots and the troches under the tongue taste terrible so if these patches work I will be happy
- stickersteve
- Thread
- Apr 29, 2019
- patches
- Replies: 2
- Forum: Testosterone Basics & Questions

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038