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  1. Vince

    VO2 Max: The Gold Standard

    AI Overview While both VO2 max and strength are strong indicators of longevity, VO2 max is considered the most robust predictor. However, strength, alongside muscle mass, plays a significant role in overall health and lifespan. VO2 Max: The Gold Standard Definition: VO2 max, or maximal...
  2. Vince

    Dosages

    Exactly we are all different and need different levels. You should read Florence's book I think you would find it very interesting and educational.
  3. Vince

    Dosages

    Calm down
  4. Vince

    Dosages

    https://www.excelmale.com/threads/why-do-some-men-need-supraphysiological-doses-of-testosterone-to-achieve-normal-levels.32512/post-298802
  5. Vince

    Dosages

    I say would say a good starting dose would be 50 mg of T and 500 IU of HCG combined in the same syringe. My understanding is that's @Nelson Vergel protocol. Here's mine. I just had Labs done yesterday will post when available...
  6. Vince

    Dosages

    No. What I mostly see is younger men need lower doses. The reason behind it is when you were at your peak. What was your T level at. Most younger men had lower levels when they were at their peak. Older men had higher levels when they were at their peak, so now the older men need higher levels...
  7. Vince

    Testosterone dropped after a few months on the same dose

    Your first labs were done after 8 weeks. Not long enough. You need to wait at least 12 weeks. So your 2nd Labs I would consider more accurate. Every time you do Labs they will vary. Injecting is not 100% accurate and of course vial strength will vary. I feel my best at higher levels so I see...
  8. Vince

    Reassessing the evidence of a survival advantage in Type 2 diabetes treated with metformin

    https://www.sciencealert.com/common-diabetes-drug-linked-to-exceptional-longevity-in-women
  9. Vince

    Clomid for Testicular Shrinkage ?

    I now inject 500 IU of HCG every third day. I combine T and HCG in the same syringe, like Nelson. It's not true about desensitization.
  10. Vince

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    That's exactly what Florence Comite talks about in her book and practice. https://en.m.wikipedia.org/wiki/Florence_Comite
  11. Vince

    Does arthritic elbow mean I can't lift weights?

    This is what worked for me. Of course it may not work for you. I had tennis elbow about 3 years ago, it was very painful. I had to resort to pull-ups and chin-ups really stretch out my elbow. It did work for me. Now I'm completely pain-free.
  12. Vince

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    AI Overview Based on the provided search results, the UGT2B17 gene plays a significant role in testosterone metabolism and clearance, specifically through glucuronidation, a process that makes testosterone easier to excrete. Individuals with a deletion in the UGT2B17 gene show reduced...
  13. Vince

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    CYP17A1: This gene plays a role in the synthesis of testosterone.
  14. Vince

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    https://www.excelmale.com/forum/showthread.php?1403-Are-you-a-fast-metabolizer-of-medicines&highlight=Fast+metabolizer
  15. Vince

    Cannabis and DHT

    When I looked it up not everyone can gets a positive reaction from cannabis
  16. Vince

    Cannabis and DHT

    Does cannabis increase your libido and orgasms?
  17. Vince

    3 hours of sleep and no fatigue?

    For decades, the mantra has been the same: adults should aim for seven to eight hours of uninterrupted sleep each night for optimal health, performance, and longevity. From doctors to wellness influencers, the message has echoed across platforms, backed by countless studies linking insufficient...
  18. Vince

    Big subjective difference between compounded hCG and Pregnyl

    Personally I never noticed a difference between the two.
  19. Vince

    Estradiol deviation for improvement or symptoms

    https://www.excelmale.com/threads/im-fed-up-with-these-mood-swings-and-sensitivity-loss.1900/ https://www.excelmale.com/threads/hormones-and-mood%E2%80%93-the-first-steps-to-feel-better.3148/ https://www.excelmale.com/threads/mood-swings.32488/
  20. Vince

    Cannabis and DHT

    Interesting, I wonder if it's true?
  21. Vince

    HCG while on TRT for testicular atrophy

    I get HCG for reliable RX and inject 500 IU every third day. I combine it in my syringe with my testosterone. It's pretty simple. I learned it from Nelson.
  22. Vince

    About to Start a New Protocol

    I'm close to your age and I have been on TRT for over 10 years. Here's my protocol. https://www.excelmale.com/threads/vinces-labs-from-october-14-2024.31363/
  23. Vince

    CARRIER OIL & HIGH HCT

    During my first 2 years of TRT, I donated blood every 8 weeks to control my HCT. After that I went to daily injections and I no longer had to donate. It's been over 8 years here since I donated blood. I don't know if it was because of daily's or longevity...
  24. Vince

    Updated Labs - Help Please

    Personally I never checked my prolactin. It's very hard to control and to get proper labs for prolactin.
  25. Vince

    6 symptoms of high cholesterol seen in body and face

    https://timesofindia-indiatimes-com.cdn.ampproject.org/v/s/timesofindia.indiatimes.com/life-style/health-fitness/health-news/6-symptoms-of-high-cholesterol-seen-in-body-and-face/amp_etphotostory/121353053.cms?amp_gsa=1&amp_js_v=a9&usqp=mq331AQGsAEggAID#amp_tf=From%20%251%24s&aoh=17480105620220&cs...
  26. Vince

    Updated Labs - Help Please

    Your labs don't look bad. I would consider going back to shallow IM. I also do daily injections, I rotate shoulders, VG and SubQ in my love handles.
  27. Vince

    Is Fiber Really Essential?

    Fiber, It also supports a healthy gut microbiome, which is important for overall well-being.
  28. Vince

    Is Fiber Really Essential?

    I believe the number one thing you need or we need. Healthy gut bacteria, probiotic and pre-probiotic. It works for me
  29. Vince

    Coming off after 10 years non stop self administered "trt" MISSION IMPOSSIBLE RECOVERY

    Just live a completely clean life and I believe you will fully recover. I know many men that did.
  30. Vince

    subcutaneous injection for treating hypothyroidism.

    I thought this was interesting. A Sub-Q injection for hypothyroidism. It's in phase 3, see what happens if it makes it to phase 4. XP-8121, a Phase 3-ready, once-weekly subcutaneous injection for hypothyroidism...
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