Vitamin E, an Antioxidant, As a Possible Therapeutic Agent for Treating Pain

seppuku · Aug 27, 2025

Vitamin E, an Antioxidant, As a Possible Therapeutic Agent for Treating Pain

Background: Free radicals are involved in many physiological functions of chondrocytes, such as intracellular signaling, apoptosis, cytokine production and extracellular matrix remodeling. However, increased oxidative stress due to the imbalance …

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Guided_by_Voices · Aug 27, 2025

seppuku said:
Vitamin E, an Antioxidant, As a Possible Therapeutic Agent for Treating Pain

Background: Free radicals are involved in many physiological functions of chondrocytes, such as intracellular signaling, apoptosis, cytokine production and extracellular matrix remodeling. However, increased oxidative stress due to the imbalance …

healthcare-bulletin.co.uk

The Vitamin E gurus emphasize that a full-spectrum Vitamin E should be used that includes all Tocopherols and tocotrienols. Chris Masterjohn recommends the Tocosorb brand.

Also, I have noticed benefit from Boswellia, something that gets very little publicity. Curcumin can help too and has other benefits.

Vince · Aug 27, 2025

Remember vitamin e is a absoluble vitamin and you can store.

Tocotrienols often offer superior benefits to tocopherols in several areas, including antioxidant activity, cholesterol regulation, neuroprotection, and anticancer potential. This is primarily due to their different molecular structure, which allows them to move more flexibly and penetrate tissues like the brain and liver more effectively.

seppuku · Aug 28, 2025

Guided_by_Voices said:
The Vitamin E gurus emphasize that a full-spectrum Vitamin E should be used that includes all Tocopherols and tocotrienols. Chris Masterjohn recommends the Tocosorb brand.

Also, I have noticed benefit from Boswellia, something that gets very little publicity. Curcumin can help too and has other benefits.

I'm currently taking a vit E supplement, (but then i've been a bit of a supplement junkie for most of my life!). It's a base of 400iu alpha tocopherol, but has mixed tocopherols in it too. I'm mainly on it again because, i take quite a bit of omega 3, but also i read about it somewhere helping with rheumatoid arthritis which i get in my thumb joint. My main supplement for that though is high dose vit D, which seems to keep things under control at the dose of 15k iu i'm on.

Curcumin, i've been taking various forms of it (Meriva, C3 etc) on and off for a while now. Never noticed anything dramatic from it with regards to joint pain, but i know the science backs it up and it's generally considered 'healthy' so i keep adding it in.

As to boswellia, that's one i keep reading about and meaning to try - have you noticed much benefit from it yourself?

I'm also looking into black seed oil - i saw a short video by Dr Eric Berg on it. He reckons it's more powerful than ibuprofen as an anti inflammatory, but then his videos do seem a bit click-baity (like most influencers i guess).

Guided_by_Voices · Aug 28, 2025

seppuku said:
I'm currently taking a vit E supplement, (but then i've been a bit of a supplement junkie for most of my life!). It's a base of 400iu alpha tocopherol, but has mixed tocopherols in it too. I'm mainly on it again because, i take quite a bit of omega 3, but also i read about it somewhere helping with rheumatoid arthritis which i get in my thumb joint. My main supplement for that though is high dose vit D, which seems to keep things under control at the dose of 15k iu i'm on.

Curcumin, i've been taking various forms of it (Meriva, C3 etc) on and off for a while now. Never noticed anything dramatic from it with regards to joint pain, but i know the science backs it up and it's generally considered 'healthy' so i keep adding it in.

As to boswellia, that's one i keep reading about and meaning to try - have you noticed much benefit from it yourself?

I'm also looking into black seed oil - i saw a short video by Dr Eric Berg on it. He reckons it's more powerful than ibuprofen as an anti inflammatory, but then his videos do seem a bit click-baity (like most influencers i guess).

The boswellia definitely seems to help me with my hip, leg and knees. I had not heard of black seed oil for inflammation but have some so I'll give it a try. For joint pain, the Gunthers methol rub and diclofenac gel both seem to help a lot, as well as BPC 157.

seppuku · Aug 30, 2025

Guided_by_Voices said:
The boswellia definitely seems to help me with my hip, leg and knees. I had not heard of black seed oil for inflammation but have some so I'll give it a try. For joint pain, the Gunthers methol rub and diclofenac gel both seem to help a lot, as well as BPC 157.

You and this article i found has convinced me to give boswellia a try -

Thread 'Boswellia the "best" supplement for pain management in knee osteoarthritis' Boswellia the "best" supplement for pain management in knee osteoarthritis - Excel Male Men's Health Forum