Lithium

Seagal · Jul 13, 2025

I'm interested in hearing about your experience with supplementing Lithium (orotate, aspartate etc).

Any feedback is appreciated.

Cataceous · Jul 13, 2025

I've been getting about a milligram daily of elemental lithium via lithium orotate for some years now. I can't claim any very noticeable effects, but it seems worthwhile to take due to the positive associations and claimed protective effects.

Seagal · Jul 13, 2025

I didn't read in depth about it and started taking 0.25mg Li orotate (liquid) in the morning. I felt like it makes me a bit tired. I then read up on potential biochemical effects and the potential GABAergic effect made sense. Now taking it in the evening.

Did any of you with tendency to depressive mood noticed any change?

Seagal · Jul 13, 2025

In case someone is interested,

there is an older thread with links to information:
Thread 'Lithium Orotate 5mg ?' Lithium Orotate 5mg ? - Excel Male TRT Forum

I find this YouTube video provides an objective brief overview with relevant details:

Guided_by_Voices · Jul 13, 2025

The anti-aging author and doctor, Dr. Sandra Kaufmann is a huge proponent of lithium. She covers it in one of her books I think and has spoken about it on several podcasts.

Vince · Jul 13, 2025

Seagal said:
I'm interested in hearing about your experience with supplementing Lithium (orotate, aspartate etc).

Any feedback is appreciated.

It sounds like it's a medication? Where are you buying it from?

Vince · Jul 13, 2025

I see both safe labs and reliable RX have lithium

Seagal · Jul 13, 2025

Vince said:
I see both safe labs and reliable RX have lithium

I'm sitting in the EU (Germany) thus I was lucky to find it on Amazon labelled for lab and research purposes.

Seagal · Jul 13, 2025

Vince said:
It sounds like it's a medication? Where are you buying it from?

It can be a medication in high doses for bipolar.
Here in this context it's about supplementing single digit mg (about 1mg). We have various small amounts in our water etc. So far lithium is not regarded essential but there is academic discussion about it and whether a small amount is beneficial.
...the video linked above explains it much better...

Cataceous · Jul 13, 2025

Vince said:
I see both safe labs and reliable RX have lithium

This isn't necessarily relevant and could get people into trouble. Some of these products contain 450 mg of lithium carbonate per tablet. Lithium carbonate is about 19% lithium, so you're talking about 85 mg of lithium. In contrast, this thread is talking about doses ranging from around 0.3 mg to 1 mg daily. Lithium orotate is only about 4% lithium by weight. Lithium orotate as a supplement is often found as 120 mg tablets that contain 5 mg of elemental lithium each. These can be quartered to get closer to the recommended range.

Vince · Jul 13, 2025

Cataceous said:
This isn't necessarily relevant and could get people into trouble. Some of these products contain 450 mg of lithium carbonate per tablet. Lithium carbonate is about 19% lithium, so you're talking about 85 mg of lithium. In contrast, this thread is talking about doses ranging from around 0.3 mg to 1 mg daily. Lithium orotate is only about 4% lithium by weight. Lithium orotate as a supplement is often found as 120 mg tablets that contain 5 mg of elemental lithium each. These can be quartered to get closer to the recommended range.

Yes, I read Seagal post. He's talking about taking 1 mg. Very small amount much smaller than they sell at reliable RX or safe Labs.