Instant Blood Pressure Spike on Starting TRT

ClashCityRocker · May 9, 2025

Systemlord said:
Come to think of it, your symptoms sound a lot like ODing on anastrozole.

You weren't prescribed anastrozole were you?

Nope. Only prescription med I'm on is T cypionate.

ClashCityRocker · May 9, 2025

SS1LE said:
To the OP, testosterone can spike your norepinephrine which will cause high bp. Which should normal out after a while.

Man, I hope so. I'm feeling less hyper, but still a little giddy. Have to watch myself at work, ha.

ClashCityRocker · May 10, 2025

Update: BP at one week trough (after 40 mg) was 121/74. For me, that is great a reading under any circumstance. Very stoked!

I'm going to try to 20 mg every 3 days for now.

I would even go less, but I'm working with kind of shitty Amazon 1mL syringes and separate 25 gauge needles (moving down from 22 gauge, ha). It's hard to use a very low dose with that set-up because the syringe just doesn't empty completely.

But I'm going to try to find some 27 gauge x 3/4" insulin pins.

Lesson learned for me: I respond strongly and need to go very slowly at first. Thank you for all the input. Very much appreciated.

FunkOdyssey · May 10, 2025

ClashCityRocker said:
But I'm going to try to find some 27 gauge x 3/4" insulin pins.

Those don't exist.

This is what you want for minimum gauge, maximum length for reaching the muscle at fattier sites like ventroglutes: Easy Touch U-100 Insulin Syringe with Needle, 27G 1cc 5/8-Inch