Came off TRT 2 years ago: my balls are much smaller than before and decreased fertility, but hormone levels are good. How can I get back to normal?

Systemlord said:

I’m not convince of this idea that high SHBG lowers FT. I can’t see a mechanism where this would be the case. Androgens lower SHBG, so low levels of androgens would see a rise in SHBG, and may be more than one factor increasing SHBG, like improvements in insulin sensitivity through fasting or starvation.

Click to expand...

I should have been more clear with a robust TT 584 ng/dL and high SHBG his cFT would be at the bottom end.

SHBG inflating his TT.

Systemlord said:

It took me about five months to start declining healthwise after I stopped TRT in 2019, erections declined over an 8 month period. This was a slow decline in overall health.

Click to expand...

I’ve already been off TRT for nearly 2 years now.

Systemlord said:

I’m not convince of this idea that high SHBG lowers FT. I can’t see a mechanism where this would be the case. Androgens lower SHBG, so low levels of androgens would see a rise in SHBG, and may be more than one factor increasing SHBG, like improvements in insulin sensitivity through fasting or starvation.

Click to expand...

It is far from a given that one will drive down SHBG when using exogenous T.

Not everyone will see a significant drop in SHBG.

Higher doses would have a bigger impact and even than the c-17 alpha-alkylated orals would hold the title when it comes to driving down let alone crushing SHBG!

My pre-trt SHBG was 34 nmol/L.

Always hovers around 30-32 nmol/L 7+ years on TTh!

madman said:

The testing method is critical!

Always include the testing method (cFT, direct)/assay used (direct immunoassay, Equilibrium Dialysis, Equilibrium Ultrafiltration) and the reference range.

Click to expand...

@Systemlord

This is the first thing you should be telling everyone on the forum that posts labs without all the critical info!

You have been on here long enough yet fail to mention this every time.

madman said:

This is the first thing you should be telling everyone on the forum that posts labs without all the critical info!

You have been on here long enough yet fail to mention this every time.

Click to expand...

madman said:

This is the first thing you should be telling everyone on the forum that posts labs without all the critical info!

You have been on here long enough yet fail to mention this every time.

Click to expand...

Fail to mention it every time? I just posted this. I haven’t posted here in forever.

I mean…thanks for the help and everything, seriously, but I don’t lurk here all the time and keep up with the requirements for posting. I’d be happy to adhere to them if I knew them…which is why I posted that info with no protest when it was asked.

JCUSN said:

Fail to mention it every time? I just posted this. I haven’t posted here in forever.

I mean…thanks for the help and everything, seriously, but I don’t lurk here all the time and keep up with the requirements for posting. I’d be happy to adhere to them if I knew them…which is why I posted that info with no protest when it was asked.

Click to expand...

This was directed at Systemlord.

madman said:

This was directed at Systemlord.

Click to expand...

Ah my bad! Sorry about that.

ok your problem is small balls relative to previous after long term trt. i had similar issue.For me it Took 2 years to get ball volume back. Its a long and slow process and i needed 3xweekly HCG ( i used recombinant HCG high dose )for the full 2 years. The stem cells from which the relevent testicular tissue recovers takes a long long time to regenerate. Longer than the actual Leydig cell function that puts out the T .