Retatrutide noob questions (order already done)

[KizzaP96]

I've decided to source some retatrutide from a Chinese supplier via platforms like Made-in-China or Alibaba, and I’m planning to order 10 x 10mg vials strictly for personal use. I'm currently on 10mg trizepitide from eli lilly and have been doing extensive research around it.


My plan is to send one vial to Janoshik for testing, provided all vials are from the same batch. Assuming the quality checks out, I intend to follow this dosing protocol:

• Week 1: 0.25mg twice per week
• Week 2: 0.25mg twice per week
• Week 3: 0.50mg twice per week
• Week 4: 0.50mg twice per week
• Week 5: 0.50mg twice per week
• Week 6: 0.50mg twice per week
  ...and so on.

From what I’ve read, a reconstituted 10mg vial only remains stable for about 28–35 days when refrigerated. Based on available information, it seems you can pre-load insulin syringes and freeze them — then thaw them in the fridge a day before use — but opinions are mixed.


Given that I’m relatively new to this, here are the concerns I currently have:

1. Is Janoshik the most reliable peptide testing service in the EU, and what is their typical turnaround time?
2. Is it safe to freeze retatrutide in preloaded insulin syringes? Some peptides degrade when frozen — does this apply to retatrutide?
3. How can I ensure sterile technique? I want to avoid contamination during reconstitution and dosing.
4. How do I verify the accuracy of micro-doses in insulin syringes? With such small doses, slight errors can matter.
5. What signs of degradation should I watch for in reconstituted or frozen peptides?
6. How should I store unopened lyophilized vials? Is room temperature okay, or should they be kept refrigerated?

 

[brookseth]

1. Yes Janoshik is reliable. about 2-4 weeks after receiving your products.
2. No, you should not freeze reconstituted peptides as this can cause degredation.
3. You use an alcohol swab on the vial and injection site, also use clean / fresh needles and syringes
4. not sure what you are asking here, you need to just make sure you draw to the correct number of units.
5. vial should just be clear liquid without and foreign substances. that being said you could have degradation or endotoxins not visible to the eye.
6. refrigerator or frozen for lyophilized vials.

Also - your dosing protocol is WAY off for retatrutide. dosing is similar to tirzepatide.

I mean this very respectfully when I say this, but you have mentioned that you "have been doing extensive research" and to be honest this post tells me otherwise.
I would strongly recommend researching further and making sure you have a more well rounded knowledge of what you are doing before self prescribing, ordering from china, and self injecting any compounds.

 

[Vince]

Sounds like an awesome drug. If retatrutide makes through trials.

If they ever make these drugs cost efficient, there never will be anyone fat again.

 

[FunkOdyssey]

Sounds like an awesome drug. If retatrutide makes through trials.

If they ever make these drugs cost efficient, there never will be anyone fat again.

This doesn't seem entirely true. Without lifestyle changes, dose escalation is required over time to maintain the effects, until eventually tolerance builds to the highest tolerable dose and weight starts increasing again even as the drug is continued. This process seems to take a few years from what I've heard, but it doesn't appear to be a life-long solution.

 

[KizzaP96]

1. Yes Janoshik is reliable. about 2-4 weeks after receiving your products.
2. No, you should not freeze reconstituted peptides as this can cause degredation.
3. You use an alcohol swab on the vial and injection site, also use clean / fresh needles and syringes
4. not sure what you are asking here, you need to just make sure you draw to the correct number of units.
5. vial should just be clear liquid without and foreign substances. that being said you could have degradation or endotoxins not visible to the eye.
6. refrigerator or frozen for lyophilized vials.

Also - your dosing protocol is WAY off for retatrutide. dosing is similar to tirzepatide.

I mean this very respectfully when I say this, but you have mentioned that you "have been doing extensive research" and to be honest this post tells me otherwise.
I would strongly recommend researching further and making sure you have a more well rounded knowledge of what you are doing before self prescribing, ordering from china, and self injecting any compounds.

I've spent 3 weeks researching it,

I've seen everywhere from starting at 2mg a week to .25mg a week, read the Eli lilly trial results also, but of course there is so much mixed information out there I don't know who to trust.

The company that's testing it in trials or the people who've actually been taking it for months.

Fucking AI added that 4th question in when I asked it to polish up what I wanted, it added like 6 silly questions but I must have missed that one.

 

[KizzaP96]

This doesn't seem entirely true. Without lifestyle changes, dose escalation is required over time to maintain the effects, until eventually tolerance builds to the highest tolerable dose and weight starts increasing again even as the drug is continued. This process seems to take a few years from what I've heard, but it doesn't appear to be a life-long solution.

That's why you use it as a tool, similar to those who are diabetic in insulin.

Ive been on a pretty strict diet since the start of trizeptide I lost like 60lbs however I have stalled in recent weeks because I've been so sick I've not left my bed really, but once I get a diagnosis from hospital and get some medication in me to fix what ever the f is up I will be straight back in the gym but at the moment I wake up with no feeling in my legs and feeling like complete ass.