Introduction and PSA lab numbers

AFSOCCRNA

New Member
Hello all. 57 and have been on TRT for a couple years, 200mg divided up into 2 x/week. Just moved and started with the VA in Arizona. Got some labs and all looked good except for a PSA of 4.3. Has been creeping up for a few years and the VA is balking at writing a script for drug. Am now working with Defy Medical which I found here and they are concerned, haven’t talked to a practitioner yet but not sure what they will say.

Had DRE by a urologist about 2.5 years ago when dealing with a kidney stone and all he mentioned was a bit of hypertrophy. Not sure if I should be looking to see another urologist yet or not.

Lots of confusing info out there re TRT and prostate care so I’m trying to get through it.
 
Just make sure you don't have a prostate infection. Most clinics will not start you on TRT at PSA equal of greater than 4 since it is a contraindication for TRT which can make them liable.
 
I've had an occasional PSA test come back high - like in the 4.7 range. My usual is 1.2 to 1.7, invariably under 2.0. Retest a few days later and the results came back at my usual normal. Doc and I discuss...and the high test results seemed to correlate to a romp in the sack with the wife the night before (and I had a whopper of an orgasm). Doc said it's plausible, so...there's that to take into consideration.

Going forward, I just make sure to abstain a couple of days before blood testing. High PSA hasn't occurred since.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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