New HDL/LDL management guidelines from American College of Cardiology

jdthoosier

Active Member
New Guidelines: 2018 ACC/AHA Multisociety Guideline on the Management of Blood Cholesterol
NY Times article: HDL Cholesterol: Too Much of a Good Thing?

  1. Instead of a cookie cutter approach to treating high LDL -C levels, tailor the treatment to the patient, with a stronger emphasis on lifestyle. Still, go-to treatment are statins for high-risk.
  2. Sweet spot for HDL is 40-60 mg, based on a u-shaped curve.
  3. No such thing as a sweet spot for LDL-C. Still a question of what adaptive benefits a higher LDL-C could provide? Concerns above 70mg for 'unhealthy' patients, 100mg for otherwise healthy.
 
And BTW, I took some of these steps as identified by the site mentioned by Vince (less red meat, more veggies/fruits, more fish, more vigorous exercise) and really improved my HDL, LDL, and cholesterol levels. It would be good however to see what the correlating inflammatory tests are like, but as mentioned, hard for me to get these tests locally.
 
And BTW, I took some of these steps as identified by the site mentioned by Vince (less red meat, more veggies/fruits, more fish, more vigorous exercise) and really improved my HDL, LDL, and cholesterol levels. It would be good however to see what the correlating inflammatory tests are like, but as mentioned, hard for me to get these tests locally.
I go through a clinic (advanced lipidology) to get my labs done from the Cleveland Heart Clinic. I had to do a lot of research to find a clinic that accept my insurance and did the proper lipid panel testing. When I originally started with them, they were out of network.
 

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Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

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Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

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The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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