To anyone taking Cialis daily — did you develop a dependence on it?

Anonymon

Active Member
Anyone been on Cialis for extended periods of time to comment on whether they became dependent on it? Granted if you had ED before taking it and it fixed it for you then I can see that being some form of dependence, but I’m mainly interested in people or anecdotes of others that have taken it daily for potentially years and could get it up before that, albeit maybe not as well, or took it for non-erection related reasons.

I’ve used it in the past and it works fine even at 5mg—probably too well—and am interested in taking it daily for the non-erection related benefits it gave me. I don’t want to develop ED years down the line if I stopped taking it, however.
 

Golfboy307

Active Member
Fair concern. What is your age?

I have been taking 3mg daily for 5+ years, but I use as part of an overall approach to boosting NO, along with being on Test therapy. Do I have a dependence on it? Perhaps, but I believe it has contributed to restoring the overall health of my penile tissue. I am 54, FYI.

I would be a lot more concerned about long term issues if I was younger.
 

Justin-5

New Member
I have definitely noticed a dependency for it. I’m 40 and originally started taking for NO purposes 5-10 mg/day. Now I notice that if I’m off of it my erections are terrible
 

Anonymon

Active Member
Fair concern. What is your age?

I have been taking 3mg daily for 5+ years, but I use as part of an overall approach to boosting NO, along with being on Test therapy. Do I have a dependence on it? Perhaps, but I believe it has contributed to restoring the overall health of my penile tissue. I am 54, FYI.

I would be a lot more concerned about long term issues if I was younger.
I’m in my 30s.
 

madman

Super Moderator
Anyone been on Cialis for extended periods of time to comment on whether they became dependent on it? Granted if you had ED before taking it and it fixed it for you then I can see that being some form of dependence, but I’m mainly interested in people or anecdotes of others that have taken it daily for potentially years and could get it up before that, albeit maybe not as well, or took it for non-erection related reasons.

I’ve used it in the past and it works fine even at 5mg—probably too well—and am interested in taking it daily for the non-erection related benefits it gave me. I don’t want to develop ED years down the line if I stopped taking it, however.

Looking at the bigger picture there is a good chance that you will suffer from some degree of ED eventually.

Aging let alone underlying vascular health will play a significant role.

If anything low dose tadalafil (daily) would have a beneficial effect on the overall health of penile tissue.


*Preliminary data suggest that products that upregulate this NO producing pathway and/or pharmacologically release NO, and/or protect its product, cGMP, show promise in halting or reversing the cellular changes associated with this aging process.




*No evidence has emerged concerning the development of any form of dependence or tolerance with the chronic use of PDE5 inhibitors.



post#7
 

DixieWrecked

Active Member
I've noticed a dependence on it. And to take it a step further I've noticed a tolerance to it. 20mg years ago would have resulted in basically non-stop rock hard erections, and now, it does very little. Sadly.
 

Golfboy307

Active Member
My doctor discussed the fact that some guys develop tolerance for the drugs and have to increase dosage to the point where its not effective anymore. His opinion is that those men continue to have vascular deterioration or plaque build up which ultimately renders the drugs less effective.

Back to OP: if you are in your 30's I would be hesitant about starting on a full course of Cialis/Viagra. I would look to other causes: Hormones, thyroid, psychological causes at your age. Do you have any signs of high blood pressure or early diabetes?

As Madman indicates, 50-70% guys will need them at some point depending on age. I just think you want to hold off as long as possible.
 

madman

Super Moderator
My doctor discussed the fact that some guys develop tolerance for the drugs and have to increase dosage to the point where its not effective anymore. His opinion is that those men continue to have vascular deterioration or plaque build up which ultimately renders the drugs less effective.

Back to OP: if you are in your 30's I would be hesitant about starting on a full course of Cialis/Viagra. I would look to other causes: Hormones, thyroid, psychological causes at your age. Do you have any signs of high blood pressure or early diabetes?

As Madman indicates, 50-70% guys will need them at some point depending on age. I just think you want to hold off as long as possible.
$$$
 

DixieWrecked

Active Member
My doctor discussed the fact that some guys develop tolerance for the drugs and have to increase dosage to the point where its not effective anymore. His opinion is that those men continue to have vascular deterioration or plaque build up which ultimately renders the drugs less effective.

Back to OP: if you are in your 30's I would be hesitant about starting on a full course of Cialis/Viagra. I would look to other causes: Hormones, thyroid, psychological causes at your age. Do you have any signs of high blood pressure or early diabetes?

As Madman indicates, 50-70% guys will need them at some point depending on age. I just think you want to hold off as long as possible.
Man, I can't imagine that is the case for me. I work out religiously (twice a year). And eat well. Fitness is my entire lifestyle. I turn 40 this year. I think I'll get a calcium scan done this summer just to see what's up. Unfortunately this is just something I have dealt with for a while. Two things happened to me in my twenties. I used to live in Bolivia. I worked in the US embassy there. This is when my use of cialis started. One day I developed a pain in my penis along the dorsal vein and I went to a Bolivian doc and he said it was a clot. He gave a cream to rub on there. Despite doubting the competency of Bolivian docs I followed the treatment and it went away. Around the same time I also did a few cycles of M1T. One day I got food poisoning and they drew blood, the blood was black. I remember thinking it looked crazy and assumed it was because I was sky high hematocrit from living at an elevation of 2 miles.

I always attributed the problem to screwing with my endocrine system with the M1T use.

Fast forward to a few years ago. I was hospitalized with a PE and diagnosed with Factor 5 Leiden. So maybe that doc was right. Perhaps there is some damage there. Regardless, a calcium scan would be interesting and Ill do it this summer.

PS: just kidding about the twice a year.
 
Last edited:

madman

Super Moderator
Ones underlying vascular health is critical!



7. Conclusions

D-PDU is an important diagnostic tool even in the era of oral drugs. We believe that the D-PDU has a fundamental diagnostic role even in the young patient with primary ED or secondary to trauma of the pelvis, perineum, and penis. Remarkably, young patients with severe anxiety show a “late-responder” penile hemodynamic pattern. In these patients, although PSV in the flaccid state may be below 13 cm/s, a normal PSV value (>35 cm/s) may be reached late (20 min) after ICI. Therefore, a D-PDU scan after ICI with vasoactive drugs should be considered a safe and accurate diagnostic test in patients with ED of any origin, while PSV in the flaccid state may not be able to investigate between different causes of vascular ED. Also, the importance of recognizing the etiology of ED has must be reinforced even in the elderly (48). In this regard, we want to remember how performing a D-PDU before the prescription of oral drugs can often be a predictor of their effectiveness (49). In fact, the data indicate that there is a correlation between the nature and severity of penile vascular damage and the response to oral drugs such as sildenafil, with a lower response observed in the presence of severe venous occlusive dysfunction or mixed ED (50).

*Finally, we want to emphasize that ED can be the first sentinel symptom for patients at vascular risk (51). The correct performance of a D-PDU is able to recognize various forms of arterial ED (52) and may be mandatory for patient's referral to the most inclusive morphological examination of the aorta, iliac vessels, femoral and carotid bifurcations, coronary arteries in search of lesions unrecognized that could save the patient's life.






This video covers how to perform a penile duplex Doppler ultrasound (PDDU). A PDDU is performed as part of the normal work-up for erectile dysfunction (ED). It helps determine if a patient’s ED is due to arterial insufficiency, venous leakage, or a combination of the two. Additionally, PDDU can be used to assess Peyronie’s disease and provides in-depth information on plaque size and location, as well as the structural abnormalities in the corpora.
 

DixieWrecked

Active Member
I'm going to look into this Madman. I really would like to get to the bottom of what the issue is. It is amazing how much sexual intimacy affects almost every part of my life. Need to find a doc in Texas that can do this. I went to one guy who advertised that he did doppler ultrasounds but all he did was listen to my heartbeat on both sides of my penis. It was nothing more than a glorified stethoscope connected to a crappy speaker. He didn't provide any type of visual imaging.
 

Anonymon

Active Member
Back to OP: if you are in your 30's I would be hesitant about starting on a full course of Cialis/Viagra. I would look to other causes: Hormones, thyroid, psychological causes at your age. Do you have any signs of high blood pressure or early diabetes?

As Madman indicates, 50-70% guys will need them at some point depending on age. I just think you want to hold off as long as possible.
I’ve never had any signs of diabetes, and my blood pressure’s historically been too low. After trying to get my iron up and other things though, my blood pressure did creep up. Still ’normal’, but at the doc I wasn’t feeling well and it was in the prehypertensive level for that day.
 

TorontoTRT

Active Member
100% there’s tolerance. I’m up to 10 mg a day cause I get it cheap. I think it should be cycled. But not sure what a good time frame cycle wise would be.
 

threeXweekstill

New Member
Regarding Cialis tolerance and effects. I am 75. I started taking it 8 years ago when I suddenly became single and wanted certainty in my performance. I also started T pellets about the same time after blood test showed moderately low T. I was and still am fairly fit and trim and now remarried. I found a Canadian source (Polar Meds) for Cialis under the brand name Tidacip, apparently manufactured in India, at less than 20% of the US pharmacy price for 20 mg strength. I began by cutting the tabs in thirds and continued that until a month ago, now cutting tabs in half (10 mg) because I began to notice an apparent reduced ED effect. I take 3 times a week. I also upped my T pellet dosage to 6 instead of 4, every 3 months instead of every 4 months (bioidentical 200 mg tabs). So far that combined program is working better. We will see how it goes since those increases are very recent. The doc put me on Anastrozol 1 mg once a week a couple of months ago. No dramatic difference in how I feel. I do bloodwork twice a year to monitor T levels. Yes, I can feel my body gradually ageing though I still work full time and enjoy a 3x week sex schedule. (If you are new to all of this and decide to go for it, be ready for a noticeable increase in your sex drive and have a willing partner). No diabetes heart or blood pressure problems. So I am not sure at this point whether I am building tolerance, or because over time I simply need more juice. I do have bph but it has been stable for over 10 years with no medication for that. I am shooting for another 5 years of success. (I have a younger wife).

It seems to me that most of the posts on this site are by guys considerably younger. I just wanted to share my experience in case some of you older guys like me are curious about all this.
 

TorontoTRT

Active Member
Regarding Cialis tolerance and effects. I am 75. I started taking it 8 years ago when I suddenly became single and wanted certainty in my performance. I also started T pellets about the same time after blood test showed moderately low T. I was and still am fairly fit and trim and now remarried. I found a Canadian source (Polar Meds) for Cialis under the brand name Tidacip, apparently manufactured in India, at less than 20% of the US pharmacy price for 20 mg strength. I began by cutting the tabs in thirds and continued that until a month ago, now cutting tabs in half (10 mg) because I began to notice an apparent reduced ED effect. I take 3 times a week. I also upped my T pellet dosage to 6 instead of 4, every 3 months instead of every 4 months (bioidentical 200 mg tabs). So far that combined program is working better. We will see how it goes since those increases are very recent. The doc put me on Anastrozol 1 mg once a week a couple of months ago. No dramatic difference in how I feel. I do bloodwork twice a year to monitor T levels. Yes, I can feel my body gradually ageing though I still work full time and enjoy a 3x week sex schedule. (If you are new to all of this and decide to go for it, be ready for a noticeable increase in your sex drive and have a willing partner). No diabetes heart or blood pressure problems. So I am not sure at this point whether I am building tolerance, or because over time I simply need more juice. I do have bph but it has been stable for over 10 years with no medication for that. I am shooting for another 5 years of success. (I have a younger wife).

It seems to me that most of the posts on this site are by guys considerably younger. I just wanted to share my experience in case some of you older guys like me are curious about all this.
Any link for that Canadian Cialis?
 

Golfboy307

Active Member
5 months is a very short time to develop tolerance for Cialis. Maybe you just found the right dosage now? Any other changes in hormones/health? Also, have you tried Viagra or Levitra?
 

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