Thanks, its still been a rough ride but I am closer and MIF-1 kinda gave me some hope. Its a gem. I hope one day HRT/peptide clinics look into this.
Gut health also seems to be important, on a Rifaximin cycle right now.
I feel like ive learned a lot about biohacking and the body in this tho and what I seem to react well to and what is horrible. Im finding that for myself when there is high inflammation, stims even caffeine worsens anhedonia/blunting. But mysteriously while on Rifaximin (which is an antibiotic staying in the small intestine for sibo, but also antiinflammatory in thr gut) caffeine actually mysteriously has the opposite effect of improving things.
Also another thing is “low cortisol issues” I think may not be directly from cortisol in many cases but a lack of cortisol response to the underlying inflammation going on
Another thing is, oversimplified but it seems the true happy chemicals are Dopamine, GABA, and opiods. I seem to respond to stuff that is dopaminergic without being noradrenergic such as Bromantane.