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  1. S

    Off antidepressant- question re anastrozole

    Through Defy Medical, I take testosterone injections twice per week. I also take anastrozole twice per week which ends up working for me. Recently, I ran out of my antidepressant citalopram (Celexa) before I realized it. I had been wanting to try and get off it any way, so I didn’t refill it...
  2. FunkOdyssey

    The Case Against Antidepressants

    I decided to create a new thread to compile some of the evidence against the use of antidepressant drugs to treat depression. In my mind, the most compelling reason to avoid them is that they may worsen the condition over time, so we will begin there. The following paper suggests poor-long...
  3. J

    HELP - Heat Rashes, ED, and Cracking Joints - A journey Riddle with Side Effects

    To preface this, I am a post-drug patient with lasting sexual side effects (yes, PFS, PSSD, and PAS exist and I will not argue this). I have had enduring sexual dysfunction (dead libido, loss of morning wood, weak erections, etc.) for about 5 years since discontinuing psychiatric drugs. Most...
  4. M

    Anyone have luck coming off TRT?

    I’m 47 years olds and suffered a depressive episode about 2 years ago. I was cycled through several Anti-depressants over several months and none worked. My testosterone was checked on 2 separate days in the morning and was found to be in the mid to low 100 range. I was started on TRT 1 year...
  5. Nelson Vergel

    The effects of six-day SSRI administration on diurnal cortisol secretion in healthy volunteers

    Send to Psychopharmacology (Berl). 2018 Dec;235(12):3415-3422. doi: 10.1007/s00213-018-5050-1. Epub 2018 Oct 3. The effects of six-day SSRI administration on diurnal cortisol secretion in healthy volunteers Ronaldson A1, Carvalho LA2, Kostich K3, Lazzarino AI3, Urbanova L3, Steptoe A3...
  6. S

    Antidepressant that increase sexual function

    Guys, I think it was Nelson that posted several weeks ago about a proposed antidepressant that could possibly increase sexual function. The post stated that it may receive approval soon, ive tried to find the post but to no avail. Any one know the name? Thanks.
  7. Nelson Vergel

    New Antidepressant Improved Sexual Function in Depressed Men and Women

    It finally got approved (Sept 2023) after years of rejections from the FDA. "Studied in over 5,000 patients, Travivo (Gepirone) has been found to have a favorable safety profile and be well-tolerated. The drug's unique single mechanism of targeted 5HT1a agonism, allows for the relief of...
  8. J

    New member November 1

    Hi. I am 46 and struggling with ED issues. I take anxiety and depression meds that have major sexual side effects. I have taken them for many years. I used to be able to "game" the system by taking a few days off the meds. Sexual function would return to normal but I'd get in a bad mental state...
  9. N

    Antidepressants hormonal effect

    I've recently stopped taking an SSRI (escitalopram) and have since noticed high estrogen symptoms. Is there any evidence and/or experience that this drug or dru class can effect estrogen levels or estrogen response?
  10. Nelson Vergel

    How to reverse sexual dysfunction caused by antidepressants

    In an open-label study of 1,022 patients with a mean 40 years of age, 59.1% reported antidepressant-associated sexual dysfunction.10 The study analyzed the following antidepressants: citalopram, paroxetine, venlafaxine, sertraline, fluvoxamine, fluoxetine, mirtazapine, nefazodone, amineptine...
  11. Nelson Vergel

    Antidepressants, Propecia and Accutane Can Cause Permanent Sexual Dysfunction

    One hundred and twenty cases of enduring sexual dysfunction following treatment The International Journal of Risk and Safety in Medicine Issue Volume 26, Number 2 / 2014 Abstract BACKGROUND: There have been reports for over a decade linking serotonin reuptake inhibitors, finasteride...
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