Penis smaller after TRT

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Antisosa

Member
34 yr male on 220mg/2weeks test cyp

I’ve been on for 3 years now. I’ve notice that over time my penis is smaller in size. Especially when not hard. Any indicators I should be looking at ? I’m going to get blood drawn in a couple weeks to see what my numbers are.
 
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Systemlord

Member
34 yr male on 220mg/2weeks test cyp
Please clarify you protocol, am I reading this right, 220mg every 2 weeks?

If this is the case, your protocol is the problem and you are on a hormone roller-coaster which produce big swings in hormones and over time the swings can get bigger and treatment becomes less effective.
 

Antisosa

Member
Please clarify you protocol, am I reading this right, 220mg every 2 weeks?

If this is the case, your protocol is the problem and you are on a hormone roller-coaster which produce big swings in hormones and over time the swings can get bigger and treatment becomes less effective.
Sorry i wrote it out wrong. My mistake. I am on 55mg e3.5d
 

Systemlord

Member
I would list any medications you are currently on (if any). Your protocol while good might not be optimal for you regardless of labs.

It would be helpful to see where SHBG currently sits along with Total T and Free T preferably using the most accurate assays, which is Equilibrium Dialysis or Ultrafiltration methods.
 

Antisosa

Member
I would list any medications you are currently on (if any). Your protocol while good might not be optimal for you regardless of labs.

It would be helpful to see where SHBG currently sits along with Total T and Free T preferably using the most accurate assays, which is Equilibrium Dialysis or Ultrafiltration methods.
This is the one I’ve ordered. Is it correct

36170-Testosterone, Free (Dialysis) And Total, MS 30289-Estradiol, Ultrasensitive, LC/MS
 

Vince

Super Moderator
34 yr male on 220mg/2weeks test cyp

I’ve been on for 3 years now. I’ve notice that over time my penis is smaller in size. Especially when not hard. Any indicators I should be looking at ? I’m going to get blood drawn in a couple weeks to see what my numbers are.
Your penis size has nothing to do with your trt levels.

Your penis size was decided in the womb.
 
Z

Zibernet

Guest
34 yr male on 220mg/2weeks test cyp

I’ve been on for 3 years now. I’ve notice that over time my penis is smaller in size. Especially when not hard. Any indicators I should be looking at ? I’m going to get blood drawn in a couple weeks to see what my numbers are.

Same exact thing here.
I've been on cream on and off for 2 years, and everytime I'm on high doses, my flacid penis size is smaller than when I'm on nothing.
Like the blood flow is diminished.
My erections are also weaker.
 

stevep

Member
Everything said about protocol, verifying labs, and can't change what you are born with is true and should be reviewed by the pro's on here. They've help me tremendously.

In my observation of my TRT journey the past several years is my daily dose of L-citrulline affects my flaccid hang. For me this jewel of a supplement makes a difference. If you're not increasing your NO maybe you should look into it after your labs are verified.
 

Neil

Active Member
If you want an alternative view, I believe its penis atrophy. Consider this, from when guys are about 13 years old, for decades their dicks are hard for hours a day. Just about every guy is masturbating or at least rock hard when a good stiff breeze blows by. Heck, in my teens and 20's I would wake up several times each and every night with a rock-hard penis. This exercises the vaso vessels in the penis thoroughly and very often. As we get older, busy with a career, waiting for wives, girlfriends, and partners that are "once a week", or too busy and just put out for a sexual workout....the penises don't get the workout they used to. Dicks atrophy, it's a fact. In short, I don't believe it's the added testosterone, you all are making an association that I don't believe is there. My recommendation is to take arginine, citrulline, daily 5mg Cialis, and start banging or jerking away or get a vacuum cylinder that you can use for at least an hour a day. You can retrain and get back most of it.

I'll give you another example. When I was in 10th grade, I broke my wrist. Back in those days they only did hard casts. That horrible sweaty cast was on me for six weeks without a break. When I got my arm back, it was pale, weak, much smaller, and looked like an old man's arm. It took months for it to look normal. That's just in six weeks. How long are you all going without daily action, the sort of daily erections that you had in your teens and 20's??

In short, get cranking, use it or lose it.
 

DixieWrecked

Well-Known Member
Interesting theory Neil and I think you are correct, but I know what the OP is talking about. My penis experiences shrinkage on TRT similar to getting into cold water. Often times very significantly. I was proud of my penis and would gladly oblige if a woman desired to reach for it but now I feel somewhat insecure about it and may even recoil from a woman's touch due to its smaller contracted appearance. Plus pde5i are much less effective. This change all happened when TRT was started.
 
Z

Zibernet

Guest
If you want an alternative view, I believe its penis atrophy. Consider this, from when guys are about 13 years old, for decades their dicks are hard for hours a day. Just about every guy is masturbating or at least rock hard when a good stiff breeze blows by. Heck, in my teens and 20's I would wake up several times each and every night with a rock-hard penis. This exercises the vaso vessels in the penis thoroughly and very often. As we get older, busy with a career, waiting for wives, girlfriends, and partners that are "once a week", or too busy and just put out for a sexual workout....the penises don't get the workout they used to. Dicks atrophy, it's a fact. In short, I don't believe it's the added testosterone, you all are making an association that I don't believe is there. My recommendation is to take arginine, citrulline, daily 5mg Cialis, and start banging or jerking away or get a vacuum cylinder that you can use for at least an hour a day. You can retrain and get back most of it.

I'll give you another example. When I was in 10th grade, I broke my wrist. Back in those days they only did hard casts. That horrible sweaty cast was on me for six weeks without a break. When I got my arm back, it was pale, weak, much smaller, and looked like an old man's arm. It took months for it to look normal. That's just in six weeks. How long are you all going without daily action, the sort of daily erections that you had in your teens and 20's??

In short, get cranking, use it or lose it.

You don't get it: when I hop on testosterone cream, within a day my flacid is small and my scrotum tight, until I discontinue.
Upon discontinuation the original size resumes.

It works like every single time I try discontinuing / resuming, it's not a "long term" thing.

Not saying your observation doesn't hold, but it's a different issue on top.
 

DS3

Well-Known Member
I am fairly certain that @Nelson Vergel has shared information about HCG and it’s potential to maximize erection size while on TRT, reversing what some males experience and refer to as decreased sensitivity and/or size.
 

DixieWrecked

Well-Known Member
You don't get it: when I hop on testosterone cream, within a day my flacid is small and my scrotum tight, until I discontinue.
Upon discontinuation the original size resumes.

It works like every single time I try discontinuing / resuming, it's not a "long term" thing.

Not saying your observation doesn't hold, but it's a different issue on top.
Do injections have this effect on you too?
 

KatyTX

New Member
L-Argine, Citrulene and 10mg of cialis. Morning and nigh, everyday. Problem solved. Vascularity fixes everything. I buy generic cialis from India. $1 per 20mg pill which I cut in half. I’m 59 and all is the same as when I was a teenager.
Look up Gene’s thread on Nitric Oxide Stack. That’s your cure.
 

madman

Super Moderator
Interesting theory Neil and I think you are correct, but I know what the OP is talking about. My penis experiences shrinkage on TRT similar to getting into cold water. Often times very significantly. I was proud of my penis and would gladly oblige if a woman desired to reach for it but now I feel somewhat insecure about it and may even recoil from a woman's touch due to its smaller contracted appearance. Plus pde5i are much less effective. This change all happened when TRT was started.

Underlying vascular health is critical.

Blood flow to the penis will have a big impact on the size when flaccid and on the strength/size when erect.


Erectile function is controlled by complex mechanisms, including the vascular and nervous systems. One of the most important materials is nitric oxide (NO). After NO is releasing in the penis, the corporal smooth muscle relaxes. However, when NO production is decreased, the erectile function weakened, resulting in ED. The relaxant system is also important for erectile function. The relaxant system is controlled by both the endothelial and the nervous systems. When the upper stream of the smooth muscle relaxant system is weakened, ED is caused; therefore, many studies have focused on smooth muscle relaxation. In contrast, corporal smooth muscle contraction is controlled by constrictors, such as noradrenaline in the flaccid state. However, if the contraction is upregulated in some situations, ED would be caused.

Interestingly, some studies have indicated that smooth muscle relaxation and contraction balance is disturbed by abnormal activation of contractile signaling pathway such as the adrenergic regulation. In some syndromes causing ED, such as diabetes mellitus or metabolic syndrome, the contraction is enhanced. One of the important contractile signaling pathways is the RhoA/Rho-kinase signaling pathway. The enhancement is known to occur in aged individuals. The inhibition of the RhoA/Rho-kinase signaling pathway by Y-27632 has been shown to improve ED in aged animal models. Interestingly, the contractility of smooth muscle in the corpus cavernosum is regulated by sexual hormones and may play a significant role in erectile function.


*In the flaccid state of the penis, which is dominated by the adrenergic tone of the smooth muscles under the influence of the sympathetic part of the autonomic nervous system, the arterial flow is low, based on the constricted arterioles and the contracted cavernosal smooth muscles




Overall, efficacy for the different PDE5 inhibitors rates is 60–70% with on-demand treatment regimens (Albertsen et al., 2010). Of the patients that initially do not respond to PDE5 inhibitors, between 30 and 50% may be converted to responders by counseling the patient and his partner. Some patients who fail to achieve an erection when taking PDE5 inhibitors on-demand benefit from a daily dosing regimen. Furthermore, in the male suffering from ED in the context of late-onset hypogonadism, the addition of testosterone supplementation might enhance PDE5 inhibitor therapy.

As the efficacy of PDE5 inhibitors depends on the integrity of the NO pathway in producing cGMP, it is evident that patients in whom this pathway is disturbed or defective will benefit far less than the general population from PDE5 inhibitors.

*Disease states that diminish NO availability include denervation of the erectile tissue following radical prostatectomy; severe diabetes with neuropathy and endothelial dysfunction; metabolic syndrome; and down-regulation of NOS expression as may be seen in atherosclerosis, aging, and hypogonadism.


An unimpaired neuronal innervation of the erectile tissue as well as intact cavernous structures, providing for the production of sufficient amounts of NO from (vascular) endothelial or neuronal sources are pivotal for the pharmacological action of PDE5 inhibitors
 

rugbyhit

Member
I was experiencing similar issues....penis didn't "hang" but shrunk up like I was in a cold bath, lousy erections, and low sensitivity. Even with cialis regimen and low dose caber (have slightly elevated prolactin) I wasn't getting much help. Added HCG (300 iu 3x wk, so 900iu total) and I'm back to good hang, good erection...like I needed HCG to get everything else to work.....also had to up my anastrozole...high E can also be a contributing factor
 

Vince

Super Moderator
I was experiencing similar issues....penis didn't "hang" but shrunk up like I was in a cold bath, lousy erections, and low sensitivity. Even with cialis regimen and low dose caber (have slightly elevated prolactin) I wasn't getting much help. Added HCG (300 iu 3x wk, so 900iu total) and I'm back to good hang, good erection...like I needed HCG to get everything else to work.....also had to up my anastrozole...high E can also be a contributing factor
I'm also a big fan of HCG, I've been injecting 500 IU twice a week now. For over 6 and 1/2 years
I really like the stuff. Plus I've never used an AI.
 
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