Yes, I have tried it all over the last 6 years. Daily doses, bi weekly, topical, injections, combination topical and injections, Test Prop, Test Cyp. It all feels like I am injecting water. Same with thyroid meds - they all feel like I am taking a placebo instead of any type of actual medication.
What if one in your situation got a liver transplant? Let's ignore the cost
I think your liver has something going on. I'm low shbg too, sometimes single digits but my problem with trt is managing e2, it's such a bitch with low shbg