Frequent urination

[cigpk]

I have recently develops frequent urination again, last time I had it was due to low e2 I believe.

Here are my labs on
40 mg test 2x a week
360 iu hcg 3x a week

Total T: 783 (362-916)
Free T: 15.7 (9-26)
E2 sens: 24 (8-35)
SHBG: 53 (15-55)
TSH: 2.1 (.45-4.5)
DHEA-S: 346 (138-475)
PSA: .9

I take 30 mg zinc, 5000 iu vit D, fish oil, 400 mg magnesium

I recently started 30 mg pregnenolone, 6 mg boron

This is increasingly becoming more of an issue. Would boron or pregnenolone worsen this?

 

[Vince Carter]

Your E2 of 24 isn't low, by the number itself, but it could be low, for YOU. Are you using DHEA or is that DHEA-S your natural level?

 

[cigpk]

That’s my natural number. At the time of the labs I was taking just the zinc, magnesium, multivitamin, fish oil and vitamin D

I recently added in the pregnenolone, boron and increased vitamin D to 5000

I’ve always had an issue with urinary frequency, even as a child. Had a prostate exam about two years ago when symptoms were worse and everything was good there. I was just told I had a small bladder.

It seems to be a little worse over the past week or so though. Maybe I just need to wait it out a little longer

 

[Checkdis]

Have you ever taken a heavy dose of Arimadex (A.I) in the past by accident?

In the end you will have to retrain your bladder. You will need a biofeedback specialist. Take a look at all my threads I have created and posted. I went through it all man but in the end there was nothing atomically wrong with me. I have 2-3 years of readings. I believe what you have is bladdder spasms which is OAB if you ruled everything out (UTI, bladder voiding, prostate, diabetes, diabetes insipidus, kidneys ). You can fix this but it takes timeeeee. Get a good urologist to rule out the crucial stuff. I never had a cystoscopy, but you can start with an MRI, CT, ultra sound, 24 hour urine diary and 24 urine test, urine culture. Are bowel movements more frequent?

What took the edge off for bad days was benzodiazepines... if that works for you... what does that tell you....

 

[cigpk]

Yeah I was told it was OAB a while ago when I was going to a urologist. I have noticed it’s worse when e2 gets low, but I’ve never taken a crazy dose of ai.

I had an ultrasound of my bladder done and it showed that I fully empty, I just always pee a lot. The worst is at night. The slightest urge to pee makes me get out of bed and use the toilet

Bowel movements are not more frequent. Just the peeing. Worse some days than others

 

[Checkdis]

Yeah I was told it was OAB a while ago when I was going to a urologist. I have noticed it’s worse when e2 gets low, but I’ve never taken a crazy dose of ai.

I had an ultrasound of my bladder done and it showed that I fully empty, I just always pee a lot. The worst is at night. The slightest urge to pee makes me get out of bed and use the toilet

Bowel movements are not more frequent. Just the peeing. Worse some days than others

I can sympathize with what you are experiencing. My advise and what I believe is you may need to retrain your bladder with biofeedback therapies. Either you are drinking too much water and not realizing it. Or you are hyper aware of your bladder and focusing on the feeling of needing to go sooner than supposed to. A 24 hour diary and 24 hour urine analysis will better show you this.

 

[CoastWatcher]

I can sympathize with what you are experiencing. My advise and what I believe is you may need to retrain your bladder with biofeedback therapies. Either you are drinking too much water and not realizing it. Or you are hyper aware of your bladder and focusing on the feeling of needing to go sooner than supposed to. A 24 hour diary and 24 hour urine analysis will better show you this.

I’m working with a pelvic physiotherapist to retrain my bladder and the muscles supporting its function. I’m 61, moderate BPH, but this is a more focused intervention. With patience, it works.

 

[Checkdis]

I’m working with a pelvic physiotherapist to retrain my bladder and the muscles supporting its function. I’m 61, moderate BPH, but this is a more focused intervention. With patience, it works.

Right, and my urologist also suggested taking Myrbetriq with these techniques. The thing with bladder medication since I have tried them all is that they just dry up my mouth. Also Vesicare and Myrbetriq are very expensive. From the two, myrbetriq was the best in my opinion.

Amitriptyline on the other hand actually worked great for me and helped with my anxiety as well and is very cheap. I would suggest trying 10mg and working up to around 50mg but nothing past that. Keep in mind a lot of these medications could run the risk of suppressing natural testosterone production.

 

[cigpk]

Yeah I’ve tried Myrbetriq and Oxybutynin

Are pelvic floor exercises similar to kegels?

 

[Checkdis]

Yeah I’ve tried Myrbetriq and Oxybutynin

Are pelvic floor exercises similar to kegels?

Yes kegels, try doing rapid fire squeezes like 20 times then 10 long reps of 5-10 second holds. And you need to do this like 2-3 times a day and be consistent. Also change your diet up, no caffeine, no alcohol, spicy foods, which I think are the heaviest on bladder triggers. There are other foods to stay away from as well if you do a google search. Gluten free diet helped me and also the Keto diet.

I have done some reading and found that people who have low estrogen or abused A.I’s have weaken the bladder walls. Since from what I have researched in these articles is that estrogen plays a huge role in the bladder wall somehow. I am still experimenting on eating foods which are higher in estrogen like grapefruit for example. And waiting to see how it changes my lab results.

 

[Nelson Vergel]

Risk Factors Affecting Decreased Libido Among Middle-Aged to Elderly Men; Nocturnal Voiding is an Independent Risk Factor of Decreased Libido - PubMed

Current cigarette smoking, frequent nocturnal voiding, and a low SHIM score were the independent risk factors for a severely low libido. K Shigehara, Y Kato, M Iijima, et al. Risk Factors Affecting Decreased Libido Among Middle-Aged to Elderly Men; Nocturnal Voiding is an Independent Risk Factor...

pubmed.ncbi.nlm.nih.gov

 

[killer]

Hi all! Has anyone had trouble urinating because of cystitis? What medications have you used to treat this condition?

 

[Nelson Vergel]

Hi all! Has anyone had trouble urinating because of cystitis? What medications have you used to treat this condition?

Check post 8

 

[Nelson Vergel]

Nocturia is affecting a lot of men. Fatigue, depression, etc happens when we do not get uninterrupted sleep.

I tend to avoid any supplements after 8 pm (B complex was making me pee a lot at night).
Spicy foods can also irritate the bladder and make me want to pee more frequently at night.
I take my blood pressure meds in the morning now instead of at night.

A teaspoon of glycine (sweet as sugar) in water makes me not only fall asleep faster but I stay asleep longer.

I also chew on two Melatonin 5 mg gummies at 9 pm.

I have very light sleep (always had).

You may want to read these:

FDA approves first treatment for frequent urination at night due to overproduction of urine - Excel Male Health Forum

The U.S. Food and Drug Administration today approved Noctiva (desmopressin acetate) nasal spray for adults who awaken at least two times per night to urinate due to a condition known as nocturnal polyuria (overproduction of urine during the night). Noctiva is the first FDA-approved treatment for...

www.excelmale.com

Waking up to urinate 2 or 3 times during the night? - Excel Male Health Forum

Anyone else experience this problem? Is this typical of an enlarged prostate? My doc said my prostate "feels" normal but it could still be enlarged. This has been an ongoing problem for the last 5 to 7 years. It seems to be getting worse. I have a urine flow test and a bladder sonogram...

www.excelmale.com

Do you get up to urinate a lot at night? - Excel Male Health Forum

Nocturia (getting up to pee frequently at night) can be caused by benign prostatic inflammation (BPH) or excessive urine production at night time. This study reviewed the pharmaceutical options to manage this issue that can impair stamina and quality of life (including erectile function) in men...

www.excelmale.com

 

[OTTO 1/2]

Nocturia is affecting a lot of men. Fatigue, depression, etc happens when we do not get uninterrupted sleep.

I tend to avoid any supplements after 8 pm (B complex was making me pee a lot at night).
Spicy foods can also irritate the bladder and make me want to pee more frequently at night.
I take my blood pressure meds in the morning now instead of at night.

A teaspoon of glycine (sweet as sugar) in water makes me not only fall asleep faster but I stay asleep longer.

I also chew on two Melatonin 5 mg gummies at 9 pm.

I have very light sleep (always had).

You may want to read these:

FDA approves first treatment for frequent urination at night due to overproduction of urine - Excel Male Health Forum

The U.S. Food and Drug Administration today approved Noctiva (desmopressin acetate) nasal spray for adults who awaken at least two times per night to urinate due to a condition known as nocturnal polyuria (overproduction of urine during the night). Noctiva is the first FDA-approved treatment for...

www.excelmale.com

Waking up to urinate 2 or 3 times during the night? - Excel Male Health Forum

Anyone else experience this problem? Is this typical of an enlarged prostate? My doc said my prostate "feels" normal but it could still be enlarged. This has been an ongoing problem for the last 5 to 7 years. It seems to be getting worse. I have a urine flow test and a bladder sonogram...

www.excelmale.com

Do you get up to urinate a lot at night? - Excel Male Health Forum

Nocturia (getting up to pee frequently at night) can be caused by benign prostatic inflammation (BPH) or excessive urine production at night time. This study reviewed the pharmaceutical options to manage this issue that can impair stamina and quality of life (including erectile function) in men...

www.excelmale.com

Nelson, what brand of melatonin gummies you are using?
Thanks!

 

[Nelson Vergel]

I use this brand : Melatonin Gummies

 

[Nelson Vergel]

One more thing. Try taking 400 mg of ibuprofen an hour before bed and let me know if you get up frequently to pee.

 

[Nelson Vergel]

J Urol. 2016 Oct;196(4):1183-9. doi: 10.1016/j.juro.2016.04.060. Epub 2016 Apr 19.

Sleep Apnea and Circadian Extracellular Fluid Change as Independent Factors for Nocturnal Polyuria

Abstract
Purpose: We investigated the relationships among nocturnal polyuria, sleep apnea and body fluid volume to elucidate the pathophysiology of nocturia in sleep apnea syndrome.

Materials and methods: We enrolled 104 consecutive patients who underwent polysomnography for suspected sleep apnea syndrome. Self-assessed symptom questionnaires were administered to evaluate sleep disorder and lower urinary tract symptoms, including nocturia. Voiding frequency and voided volume were recorded using a 24-hour frequency-volume chart. Body fluid composition was estimated in the morning and at night using bioelectric impedance analysis. Frequency-volume chart data were analyzed in 22 patients after continuous positive airway pressure therapy.

Results: Patients with nocturnal polyuria showed a higher apnea-hypopnea index (33.9 vs 24.2, p = 0.03) and a larger circadian change in extracellular fluid adjusted to lean body mass (0.22 vs -0.19, p = 0.019) than those without nocturnal polyuria. These relations were more evident in patients 65 years old or older than in those 64 years or younger. A multivariate linear regression model showed an independent relationship of nocturnal polyuria with the apnea-hypopnea index and the circadian change in extracellular fluid adjusted to lean body mass (p = 0.0012 and 0.022, respectively). Continuous positive airway pressure therapy significantly improved nocturnal polyuria and nocturia only in patients with nocturnal polyuria.

Definitions:

Nocturnal polyuria is a syndrome where the usual day to night ratio of urine production is altered. In patients with nocturnal polyuria, 33% of the total daily urine output occurs at night, although the daily total urine output remains normal.

Nocturia is a condition that causes you to wake up during the night to urinate. This can be thought of as nocturnal urinary frequency — having to urinate more often at night. This condition becomes more common as people age and occurs in both men and women, sometimes for different reasons.

 

[Nelson Vergel]

How Many Times a Day Should You Pee?​