Anastrazole and other ai’s may activate the estrogen receptor in place of estradiol

JA Battle

Active Member


Active Member
Interesting read. Does this mean that anastrozole is better or worse than exemestane/letrozole for men on TRT? I've tried both anastrozole and exemestane. Anastrozole was stronger and brought my E down more.

JA Battle

Active Member
the “zoles” would both fit this ticket potentially, but possibly letrozole to less of a degree.

anastrazole exerts it’s effects similarly to DHt as it actually converts into a rather potent androgen.

I’m not sure which is better or worse. I have never taken an ai. I tend to have rather low estradiol numbers. I periodically experiment with supplementing estradiol.

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