Would my wife benefit from HRT with those numbers?

johann

Member
My wife just got her lab test.

Testosterone 30ng/dl

Free Testosterone 1,3 pg/ml

Estradiol 41,9 pg/ml

Progesterone 2,5 ng/ml

She took the Blood test on day 1 of her period. (I think its called the Follicular phase)

And she is 47 years old.
 
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How old is your wife? Dr. Saya treats a reasonable number of women, perhaps he can offer some ideas. As an aside, the Mayo Clinic states the testosterone range for adult women as 15-70 ng/dl. Is this clinically sensible? I couldn't say.
 
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Johann - based on her age, your wife is approaching (sooner or later) menopause, with the average age range typically 45-55 years old. However, menopause is not an event, but more of a GRADUAL process whereby the ovaries shut down their hormone production (this process can occur over the span of weeks, sometimes months, or even years).

Symptoms vary depending on the specific hormone deficiencies, by include:

- night sweats, hot flashes, vaginal dryness/painful intercourse, dry skin, dry/achy joints (estrogen)

- lower concentration, "foggy" or scatter-brained" (as women often quote), poor sleep, anxiety (progesterone, also some interplay with other hormones)

- low libido, poor arousal/sexual satisfaction, low energy, poor recovery, loss of muscle mass or difficulty maintaining/gaining muscle mass, increase in fat, low mood/depression, lack of motivation/ambition, etc (testosterone)

Hope this helps. Symptoms help guide treatment equally if not more so than the lab results.
 
I always wonder why, some women lose their sex drive and libido after menopause. While other women it actually increases their libido and sexual pleasure.
 
Hi dr Saya,

No this did not help:)
I know she is getting closer to menopause, and all that will kick in.

My question is with here's current hormone profile if she would benefit from some help.

Thanks
Johann
 
Hi dr Saya,

No this did not help:)
I know she is getting closer to menopause, and all that will kick in.

My question is with here's current hormone profile if she would benefit from some help.

Thanks
Johann

Dr. Saya mentioned that symptoms are at least as important as lab results. Perhaps, if you shared some of the issues she is dealing with, he could offer more focused thoughts.
 
Without knowing symptoms (or lack thereof) it's difficult to say conclusively. Based on age and current levels it is likely she would benefit. A full consult/evaluation would determine with certainty.
 
Hard to get fat off, low mood/depression, not as powerful/motivation in the gym. According to your list of symptoms, these things are the only things she is showing signs of. The depression and low mood comes with menstruation cycles only. Is it better to start HRT now or should she wait until symptoms get worse? (after menopause starts)
 
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hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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