Which supplements should be taken on a empty stomach?

Nelson Vergel

Founder, ExcelMale.com
The breadth of available dietary supplements lining store shelves can overwhelm even the most enthusiastic of fitness folks with (often hyped-up) health claims. Important questions–such as those having to do with how or when to take your supplements to maximize nutritional benefit–are often neglected for the “if I take it, it’s good for me” mentality. Timing your supplements appropriately and being aware of possible interactions (with medications or other supplements) can not only help you optimize your supplement’s benefit but also avoid side effects.
In this article, we review the available evidence on how to time your supplemental intake for maximal efficacy, with special focus on multivitamins, minerals, fish oil, and probiotics. The image below summarizes our findings.

https://labdoor.com/article/a-guide-to-timing-supplement-intake
 
I take most of my supplement with a fatty meal, but I do take my thyroid Armour on a empty stomach and I won't eat anything for at least 45 minutes. I also take my probiotics on an empty stomach. But I do get all my levels checked.
 
Most, if not all, amino acids should be taken on an empty stomach as well but can lead to gastrointestinal distress...in other words, diarrhea.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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