When to collect saliva test while on hydrocortisone

[Gianluca]

I'm on Hydrocortisone 3 times daily and I'm testing saliva cortisol, when should I collect the specimen?

 

[LTChris]

I have read that you need to be off of the HC for a couple of weeks to get a accurate measure. Stopthethyroidmadness.com has info on this. What does your doctor suggest. I can't get the website to come up to get the link for you.

 

[ratbag]

I'm on cortisol too and I've been told to do the saliva vials just before I take my cortisol. Same timing applies to all...
8:00am
12:00pm
6:00pm
Bedtime

 

[Gianluca]

I was able to hear back from Defy, they recommend to take the sample 1-2Hr after my HC dose, that make sense, to see level of absorption

 

[ratbag]

That completely defeats the purpose of 4 x diurnal testing. The ranges are determined at these times only:
8:00am
12:00pm
6:00pm
Bedtime

These periods can't change... and changing your dosing time to accomodate that makes no sense either.

 

[Gianluca]

That completely defeats the purpose of 4 x diurnal testing. The ranges are determined at these times only:
8:00am
12:00pm
6:00pm
Bedtime

These periods can't change... and changing your dosing time to accomodate that makes no sense either.

there will be no change in dosing time, I would just collect saliva about 2Hr after taking HC which peaks in about 1Hr, more like 10am/2pm/6pm bedtime, what would be the purpose of testing cortisol levels while on HC then? I don't think it will solely show the body production of HC but I think it is useful to see how the body absorb it and metabolize it, to see if I would need more or less