Weight Training Can Increase Liver Enzymes

I agree and can vouch for this as I’ve seen it happen on my own results multiples times when I workout the night before my labs. Usually it’s the AST that increases for me.
 
ALT will be increased significantly along with LDH. GGT is not affected. ALT has a longer half life in circulation and will take longer to return to baseline. Always have them run CK along with the LFTs. If all are elevated and it concerns the practitioner, then take 7 - 10 days off all resistance exercise or eccentric style movements (downhill running) and repeat everything. The decrease in CK should parallel the decreases in AST/ALT if it is muscle origin. My AST/ALT have been in the 80's - 100's for decades and CK around 2000. If I take a week off ALT/ALT are in the 50's and CK down to 1000. If I could handle 3 weeks off everything would be back to baseline.
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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