Warning about Indian Enclomiphene tablets

Forty2

Active Member
Just a heads up about the "enclomiphene" sold in India under the brand of "En-Clofert".
When I sent an email enquiry to alldaygeneric.com to ask if they accept prescriptions from foreign doctors, they quickly replied that they do and that En-Clofert was in stock and ready to ship to me as soon as they received a copy of my prescription and payment.
I then asked them in my next email if En-Clofert was 100% Enclomiphene or if it contains some Zuclomiphene. More than one week has gone by and they have not replied to this email. Three days ago I sent them another email with the same question, just in case they did not receive my other email and they haven't replied to that one either.
On the photo that they sent me of En-Clofert, "Clomiphene Citrate 50mg" is printed on the back of the blister pack, which makes it confusing. I believe that En-Clofert is in fact really just clomiphene citrate, or at best contains just a little less zuclomiphene than clomiphene citrate, so should be avoided by those wanting to buy only Enclomiphene Citrate.
 
... I have read many reports from guys complaining of joint/bone pain from enclomiphene due to the fact that it acts as anti-estrogen everywhere in the body. ...
If enclomiphene acted as an "anti-estrogen everywhere in the body" it would not be a SERM. The "S" stands for "selective". The fact that clomiphene acts largely as an estrogen in bone and liver suggests that enclomiphene is at worst neutral in these tissues. Clearly enclomiphene is easily capable of overriding zuclomiphene at certain estrogen receptors, such as in the hypothalamus and pituitary.

An explanation that's been floated for these problematic anecdotal reports is that a dubious source of enclomiphene was used, and an aromatase inhibitor was substituted for actual enclomiphene. I can't find the post now, but someone was saying that blood work frequently supported this proposition, with estradiol appearing to be suppressed.

In any case, my experience with Tailor Made's enclomiphene was without such problems, and estradiol was definitely not suppressed.

See also:
 
If enclomiphene acted as an "anti-estrogen everywhere in the body" it would not be a SERM. The "S" stands for "selective". The fact that clomiphene acts largely as an estrogen in bone and liver suggests that enclomiphene is at worst neutral in these tissues. Clearly enclomiphene is easily capable of overriding zuclomiphene at certain estrogen receptors, such as in the hypothalamus and pituitary.

An explanation that's been floated for these problematic anecdotal reports is that a dubious source of enclomiphene was used, and an aromatase inhibitor was substituted for actual enclomiphene. I can't find the post now, but someone was saying that blood work frequently supported this proposition, with estradiol appearing to be suppressed.

In any case, my experience with Tailor Made's enclomiphene was without such problems, and estradiol was definitely not suppressed.

See also:

Ok that's good to know. Unfortunately, I live outside the US, so sourcing legitimate enclomiphene is a challenge
 
Every time I used AllDayChemist I had to have my credit card replaced, 3 times. And, the quality on the Cialis was substandard.
 

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Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

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