Want to Slow Aging? (Testosterone Could Be the Answer)

madman

Super Moderator

In this episode, Dr. Morgentaler and Dr. Brandon talk about how testosterone therapy can improve biological aging by enhancing vitality, reducing health risks, and potentially reversing some aging markers in men with low testosterone levels.




Chapters:


00:18 Understanding Biological vs. Chronological Age: The hosts explain the difference between biological age, which reflects overall health and disease risk, and chronological age, determined simply by years lived.

03:18 Testosterone's Impact on Vitality and Energy: Testosterone deficiency is linked to feelings of fatigue, irritability, and a diminished sense of vitality, which can be reversed with therapy, improving overall energy and quality of life.

07:32 Scientific Studies on Testosterone and Aging: Key studies highlight how testosterone upregulates the anti-aging Klotho gene and improves epigenetic markers, potentially reducing biological age and associated health risks.

13:27 Risks of Low Testosterone Levels: Low testosterone is associated with serious health risks, including increased chances of diabetes, obesity, osteoporosis, heart disease, and even aggressive prostate cancer.

19:55 Testosterone Therapy and Practical Advice: The episode concludes with practical insights on testosterone therapy, emphasizing its potential as a reversible trial to improve health while addressing misconceptions about long-term dependency and fertility concerns.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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