Vitamin B6 toxicity

[nuclear]

I’ve developed a neuropathy thought to be from B6 toxicity. B6 levels were three times the max of the normal range. After a thorough neuromuscular work up, this is the only identifiable possible cause. Gabapentin is the only thing that takes the edge off the pain. Opening the thread to alert everyone to this toxicity and to start discussion.

 

[Gman86]

Are you supplementing with B6?

 

[nuclear]

Yes, I was using a B complex. Plus, many supplements, bars, drinks, etc. contain B6.

 

[Gman86]

Well at least the solution is an easy one, obv stop the supplements lol. But thanks for the post, interesting to see what too much of even a b vitamin can do.

 

[FeelingLost]

I've always hated B6 it gives me extreme hunger pains.

 

[nuclear]

B6 being a water soluble vitamin is thought by many not to accumulate in the body. It does and can take a long time to clear. Neuropathy it causes can be permanent. Be careful with your intake. You only need @2 mg per day.

 

[Vince]

B6 being a water solvable vitamin is thought by many not to accumulate in the body. It does and can take a long time to clear. Neuropathy it causes can be permanent. Be careful with your intake. You only need @2 mg per day.

I agree but its a water-soluble vitamin, I believe it's almost impossible to have too high a limit. Drink lots of water.

 

[nuclear]

The neurologist said it accumulates in the muscle and can take a year or more for neuropathy symptoms to resolve, if they resolve at all. It’s a serious toxity. Be advised.

 

[Mountain Man]

Energy drinks and 5 hour energy are loaded with B vitamins. Use sparingly, especially the 5 hour energy, and don't supplement with B vitamins.

 

[Vince]

This is what I found on Vitamin B6 or P-5-P. Keep your doses low as it can potentially overdrive the CBS pathway and result in excessive sulfite level which is not good thing. The data is unclear what if any effect CBS+ has on homocysteine levels. Sulfate test strips will quantify that for you if you are interested in pursuing that pathway further.​

 

[RalphMcDonald]

Vitamin B6 causes neuropathy at intake of 1000 mg for every day or more. There have been additionally reports of toxicity at intakes of 100-300 mg for every day. The US specialists specifies level of intake at 200 mg for every day and the safe upper limit at 100 mg for each day. However, everyone need to remain alert to the high intakes of vitamin B6 as a cause of unexplained neuropathy.

 

[Wuops]

I read somewhere that even excessive amounts of water soluble vitamins can be bad.

 

[pqteb1r]

Vitamin B6 causes neuropathy at intake of 1000 mg for every day or more. There have been additionally reports of toxicity at intakes of 100-300 mg for every day. The US specialists specifies level of intake at 200 mg for every day and the safe upper limit at 100 mg for each day. However, everyone need to remain alert to the high intakes of vitamin B6 as a cause of unexplained neuropathy.

After reading this thread back in 2018 I connected lumbar pain and numbess in hands with excess pyridoxine ( B6 ) intake and avoided supplements and foods with it as an ingredient.

Recently I had the worst ever bouts of lower lumbar pain which seemed to come out of nowhere. I had been consuming multiple cans FoucusAid ( 1.7 mg 100% DV per drink ) from LifeAid. Three to five times the DV might be harmless to most but I suspect that there are those like myself who are sensitive to it. How much more was I getting from natural sources?

Pyridoxine toxicity can creep up on you. I strongly recommend NOT supplementing pyridoxine B6 and avoiding drinks and energy bars with added pyridoxine especially if your diet is already high in B6 which is easy if you eat healthy high protein foods and leafy greens.