ViraLite: an ultracompact HIV viral load self-testing system with internal quality control

madman

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In conclusion, ViraLite demonstrates a sensitive, portable approach to self-directed HIV VL monitoring enabled by multiplex RT-LAMP, machine-learning–based fluorescence analysis, and semi-automated, battery-powered electronics. The system integrates sample preparation, multiplex detection, and smartphone-guided operation into an accessible testing platform. Evaluation using archived clinical samples demonstrates real-world feasibility by pairing reliable clinical data with portable hardware. By lowering barriers to frequent VL assessment, ViraLite has the potential to increase monitoring frequency, support improved ART management, reduce transmission risk, andenable more patient-centered HIV care.
 

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