Understanding the role of estrogen in the development of benign prostatic hyperplasia

[madman]

Conclusion

BPH is a non-malignant enlargement of the prostate that affects a significant population of men above 50 years with substantial effect on quality of life. The actions of estrogens, as mediated by estrogen receptors, appear to contribute to the development of BPH in men through an intricate molecular process that is yet to be fully elucidated. Although surgery remains the gold standard in the treatment of BPH, understanding the elusive role of estrogen in BPH, in addition to the established role of androgens, would enhance the current therapeutic options and perhaps lead to the development of new therapies. Therapeutic use of phytoestrogens could be further explored to better harness phytoestrogens in the prevention and management of BPH.

 

[Tommy Wall]

As a layman like me I have some trouble to get the point really therefore could you pls simplify the message a bit. Thx!

 

[Deleted member 16042]

As a layman like me I have some trouble to get the point really therefore could you pls simplify the message a bit. Thx!

Estrogen could be a significant contributory factor in BPH. More research is needed. Phytoestrogens may provide useful treatments for BPH.

 

[Nashtide]

This could be an example of why men on TRT need to be concerned about high E2 levels even in the absence of symptoms. It just stands to reason that there has to be a level above which estrogen has negative health effects on men. I have no idea if that is the case here, but the prevailing opinion that high E2 is harmless in the absence of symptoms is probably not true.

 

[Tommy Wall]

That´s how I also understand the article

 

[Tommy Wall]

I´m bit surprised that this tread still has so few comments. I think this matter or news is highly importance or?

 

[Nik]

Si para mi es importante , no se manejar muy bien el sitio pido disculpas si publico en lugares q no tiene q ser . Q piensan sobre los hallazgos o relacion del omega 3 con el cancer de prostata