madman
Super Moderator
Conclusion
BPH is a non-malignant enlargement of the prostate that affects a significant population of men above 50 years with substantial effect on quality of life. The actions of estrogens, as mediated by estrogen receptors, appear to contribute to the development of BPH in men through an intricate molecular process that is yet to be fully elucidated. Although surgery remains the gold standard in the treatment of BPH, understanding the elusive role of estrogen in BPH, in addition to the established role of androgens, would enhance the current therapeutic options and perhaps lead to the development of new therapies. Therapeutic use of phytoestrogens could be further explored to better harness phytoestrogens in the prevention and management of BPH.
BPH is a non-malignant enlargement of the prostate that affects a significant population of men above 50 years with substantial effect on quality of life. The actions of estrogens, as mediated by estrogen receptors, appear to contribute to the development of BPH in men through an intricate molecular process that is yet to be fully elucidated. Although surgery remains the gold standard in the treatment of BPH, understanding the elusive role of estrogen in BPH, in addition to the established role of androgens, would enhance the current therapeutic options and perhaps lead to the development of new therapies. Therapeutic use of phytoestrogens could be further explored to better harness phytoestrogens in the prevention and management of BPH.
