TRT and Creatinine

Mike402

New Member
For the past 15 years my creatinine has been high. Usually the lab cut off is 1.33, and mine is over, up to 1.46. All other kidney labs (BUN) are normal. I have had 4 ultrasounds, all normal. I ve been to two kidney doctors and a Urologist. Found no causes. I ve had several urine tests, 24 hour collections. Always normal. No protein in urine. I take 200 mg testosterone cypinate every 10 days due to peaks and very bad valleys. One of the kidney docs said “there are no testosterone receptors in the kidneys” so that’s not the cause. He believes from working out and breaking down muscle is the issue and said don’t worry about it. Anyone have an opinion on could TRT be hurting my kidneys? Thank you.
 
For the past 15 years my creatinine has been high. Usually the lab cut off is 1.33, and mine is over, up to 1.46. All other kidney labs (BUN) are normal. I have had 4 ultrasounds, all normal. I ve been to two kidney doctors and a Urologist. Found no causes. I ve had several urine tests, 24 hour collections. Always normal. No protein in urine. I take 200 mg testosterone cypinate every 10 days due to peaks and very bad valleys. One of the kidney docs said “there are no testosterone receptors in the kidneys” so that’s not the cause. He believes from working out and breaking down muscle is the issue and said don’t worry about it. Anyone have an opinion on could TRT be hurting my kidneys? Thank you.
Do you use Creatine?
 
The more muscle you have the higher your creatinine will come back. It will come back even higher if you worked out before your your blood draw. Since I started TRT I have put on about 10-12 pounds of muscle. Therefore my creatinine has gone up. One time I knocked out a leg day before my blood draw and my creatinine was at 1.7.
 
The closer I do labs, after working out, the higher my creatinine levels are. I once had labs one hour after working out, I had very high creatinine levels.
 
No. Because if I don't work out before my blood draw it will be lower. I make sure I am hydrated as well. I also make sure I am consuming enough sodium. Both of these things will add volume to blood. In other words, I make sure my blood is diluted and not dehydrated and thick. Dehydrated thick blood will make your numbers look shitty
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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