Trimix loosing effect

centralwaguy

New Member
So I have a question to see if there's other people that have had similar issue I'm a 66 year-old male on no medications other than trimix or currently quad mix
My testosterone level is at 661
I had a radical prostatectomy about 3 years ago partial nerve-sparing
for the first eighteen months or so I had absolutely no activity naturally was using trimix
the trimix worked excellent I used 15 units which is .015 mils then after about 18 months I started getting some natural erection activity not adequate enough for intercourse but things were changing
as the natural erections for lack of a better term started the trimix started becoming less effective increasing the dosage did not seem to help
my doctor did a check manually said there was no scarring that she could detect and when I pump I still get the same results as far as the thickness girth and length
I have talked with two Physicians both of them are rather perplexed on why the trimix is not working as well especially in light of the fact that I'm starting to get some natural activity it should be going the other way needing less trimix
I have tried quad mix and that does not seem to help too much more
slightly better but still not like to try mix was initially
Has anybody heard of this or had it happened with them
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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