Total T high but no change

Frustrated OM

New Member
Have been on TRT for 8 weeks and have seen zero improvement if anything my symptoms have gotten worse, libido is almost nonexistent, constant fatigue, zero and i mean zero energy, have gained 10 lbs in 8 weeks while being on TRT. my dosage is
80mg or .40ml twice a week for a total of 160 mg of Test CYP nothing ese in my TRT program.

Pre- TRT Total T was 369

8 week blood work:
TT 1130 ng/dl
FT 30 ng/DL
SHBG 28 ng/dl
E2 45

I cannot get another appt with my online prescriber for another 6 weeks, but at this point i am not sure I want to continue the same path for another 6 weeks.
 
I view it as malpractice to start someone on such a large dose of testosterone. This is not TRT. Replacement amounts would consist of 40-100 mg of testosterone cypionate per week in divided doses. Many guys do not fare well with such excess:
 
Have been on TRT for 8 weeks and have seen zero improvement if anything my symptoms have gotten worse, libido is almost nonexistent, constant fatigue, zero and i mean zero energy, have gained 10 lbs in 8 weeks while being on TRT. my dosage is
80mg or .40ml twice a week for a total of 160 mg of Test CYP nothing ese in my TRT program.

Pre- TRT Total T was 369

8 week blood work:
TT 1130 ng/dl
FT 30 ng/DL
SHBG 28 ng/dl
E2 45

I cannot get another appt with my online prescriber for another 6 weeks, but at this point i am not sure I want to continue the same path for another 6 weeks.
You're overdosed, too much T can be as bad as not enough. You better make certain all vitamins and minerals are healthy before undertaking TRT, especially iron, because TRT utilizes more iron to create more hemoglobin.

Ferritin and iron saturation is the gold standard for testing iron status.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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