Tired , iritable , sleep problem on TRT

[Damian]

I have got problem with my trt. I am on 60 mg twice a week+ 250 ui hcg twice a week. My T level is about 750 ng/dl e2 is about 30. Been on this regimen for last 8 moths . I am very iritable, tired during the day , got problems with sleep, waking up during the night. Sometimes I need to go sleep during day time, lose penis sensivity but erection are very hard . Sometimes i feel joint pain or back ache. My skin is a little bit dry mainly on face.

Is it possible that my oestradiol is to Low for this level of testosterone. Should i increse dose of hcg mayby ? My t3 t4 tsh are ok i chesked them using Nelson tips.

 

[ERO]

Perhaps, is your E2 level measured via the Sensitive Assay?

It likely would not hurt to try 500 IU of HCG twice a week, wait at least 5 weeks with no other changes and then test again, and of course pay close attention to how you feel.

 

[Damian]

Ok tkank you for your advice ERO
There is no sensitive estradiol lab test in my country.
There was a lot of topics about a ratio of keeping E2 (14-20). My T:E ratio is higher than 20. Mayby this is the problem.

 

[johndoesmith]

Ok tkank you for your advice ERO
There is no sensitive estradiol lab test in my country.
There was a lot of topics about a ratio of keeping E2 (14-20). My T:E ratio is higher than 20. Mayby this is the problem.

What's the range on your E2 test?

Do you have an shbg level?

It's entirely possible your E2 test is overestimating and you are in fact low E2. You sound like that's possible due to the symptoms you listed.

It's hard to say exactly.

 

[HarryCat]

HCG at 250IU's twice a week wrecks my sleep. I skipped an HCG injection one day and that night (4 days from my last HCG injection) and the following nights I slept better. I may try doing something like 100IUs daily and see if that works better.

Couldn't hurt to skip one or 2 HCG injections and see how you sleep.

Are you taking DHEA or pregnenolone? Sometimes those can help with sleep.

 

[Damian]

I will check shbg and all hormonal panel next week and give you the answer. Range is 11-52

 

[Damian]

No, i am taking only testosteron + hcg and multivitamin suplement , vitamin C 2 g per day , magnesium and omega 6.

First 2 nights after hcg injection are also the worst for me. But without hcg i also got sleep problem. My next problem are headaches .

 

[Damian]

I got my SHBG test.

SHBG

18,50

nmol/l

10

57

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