The WHI: A Focus on Hormone Therapy (aka Lies, Damn Lies, and Statistics)

[madman]

 

[madman]

 

[madman]

Feeling confident prescribing HRT and Reclamation of Testosterone - Excel Male Health Forum

www.excelmale.com

 

[Nelson Vergel]

This study fed all fears currently held by doctors about hormone replacement. Totally irresponsible and they should retract it.

 

[madman]

 

[Nelson Vergel]

View attachment 22878

I love this!

 

[madman]

 

[madman]

Thread 'FDA Expert Panel on Menopause and HRT Recommends Removing Black Box Labels'

Jul 17, 2025

This was a very important meeting with top experts that are trying to change guidelines. This FDA panel recently recommended removing the warning (“black box”) labels on menopausal HRT, citing potential benefits like reduced heart attack and bone fracture risk—and arguing the warning discourages appropriate use.

FDA Expert Panel on Menopause and Hormone Replacement Therapy for Women​

Hopefully, we will see progress in this field after the confusing and sometimes misleading conclusions of the WHI (“Women’s Health Initiative”), a large National Institutes of Health trial...

• madman
• menopause; hrt; estrogen; testosterone; health
• Replies: 16
• Forum: HRT in Women

 

[madman]

Thread 'What Really Happened at the FDA Menopause Panel'

Jul 24, 2025

The FDA finally held a hearing on menopause—and it was long overdue. Georgie Kovacs breaks down the powerful expert testimony, the systemic failures, and why this matters for every woman navigating midlife care.

In this grounded recap, you’ll learn:

• Why the FDA’s black box warning on vaginal estrogen may be misleading

• The difference between systemic and local hormone absorption—and why it matters

• How testosterone access for women remains limited despite clear clinical need

• What experts like Dr. James...

• madman
• menopause; hrt; fda; women's health
• Replies: 8
• Forum: HRT in Women

 

[madman]

Thread 'Initiating the Removal of the “Black Box Warning” on Hormone Replacement Therapy'

Nov 23, 2025

FDA Commissioner and subject matter experts from the Center for Drug Evaluation and Research discuss the agency's recent announcement regarding removal of the “black box warning” for hormone replacement therapy.








Proposed Changes Related to Safety Information Labeling

Proposed Changes for All MHTs (Systemic and Local Vaginal Products)

Additional Proposed Changes for Systemic Products

Additional Proposed Changes for Local Vaginal Estrogen Products

• madman
• menopause; hrt; estrogen; fda/black box
• Replies: 2
• Forum: HRT in Women

 

[madman]

Thread 'Menopause, Estrogen & the FDA: What Experts Say Needs to Change'

Dec 9, 2025

The FDA just held a hearing on menopause—and experts say it’s time to rethink hormone labels. Dr. James Simon joins Fempower Health to explain what needs to change and what it means for women.




Chapters:

00:00 Intro – Why This Conversation Matters
00:14 Why Estrogen Labels Matter
00:20 Testosterone: The Missing Option for Women
06:31 Vaginal Estrogen: Creams, Rings & Pills
18:18 Breast Cancer, BRCA & Safety
26:47 Why Experts Say No New Studies Are Needed
30:07 Georgie’s Story: Vaginal...

• madman
• menopause; estrogen; fda; women's health
• Replies: 1
• Forum: HRT in Women

 

[madman]

Thread 'Cardiometabolic Health: Do Sex Steroids Matter?'

Jan 2, 2026

"Cardiometabolic Health: Do Sex Steroids Matter?" which looks at the role sex steroids play in cardiovascular health across the lifespan.




Susan R. Davis

My team who have contributed to the work presented

Conclusions

• madman
• menopause; hrt; estrogen/testosterone; cvd
• Replies: 27
• Forum: HRT in Women