The stronger your legs the better your cognition in old age

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Nelson Vergel

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The Brain & Leg Muscles in Older People

Fitter Legs Mean A 'Fitter' Brain: Leg Strength Could Also Indicate Your Cognitive
Health.
Fitter Legs Mean A 'Fitter' Brain: Leg Strength Could Also Indicate Your Cognitive Health.

They found that leg power was a better predictor of cognitive change than any other lifestyle factor they looked at.


Kicking Back Cognitive Ageing: Leg Power Predicts Cognitive Ageing after Ten Years in Older Female Twins

A striking protective relationship was found between muscle fitness (leg power) and both 10-year cognitive change (fully adjusted. Conclusion: Leg power predicts both cognitive ageing and global brain structure)

Muscular power, especially in the legs — which are the largest muscles in the body — is widely accepted as a marker of healthy aging. Older people with relatively powerful leg muscles get around better than those with weak legs. They also tend to have sharper minds, studies show.

Brawn and Brains

Can Running Make You Smarter?

Exercise Makes Our Muscles Work Better With Age


Exercise Makes Our Muscles Work Better With Age

“…..new study, which was published last week in the Journal of Applied Physiology, researchers from McGill University in Canada and other schools contacted 29 world-class track and field athletes in their 80s and invited them to the university's performance lab. …..Muscles consist of fibers, each attached to a motor neuron in our spinal column by long, skinny nerve threads called axons. The fiber and its neuron are known as a muscle unit. When this muscle unit is intact, the neuron sends commands to the muscle fiber to contract. The muscle fiber responds, and your leg, eyelid, pinky finger or other body part moves…..Using mathematical formulas involving muscle size and electrical activity, the scientists then determined precisely how many muscle units were alive and functioning in each volunteer's leg muscle. They also examined the electrical signal plots to see how effectively each motor neuron was communicating with its attached muscle fiber…..More interesting to the researchers, the athletes also had almost 30 percent more motor units in their leg muscle tissue, and these units were functioning better than those of people in the sedentary group”
 
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Defy Medical TRT clinic doctor
Do people with loss of cognitive capacity walk less and have more leg muscle wasting? Or do people with stronger legs because they use them more through life have brains that age more slowly? Good questions!

Frailty has been associated with low leg strength. In fact, leg strength seems like the best predictor to age-associated frailty.
 
Sao Paulo Med J. 2012;130(2):102-8

Relationship between lower-limb muscle strength and frailty among elderly people.
Batista FS1, Gomes GA, Neri AL, Guariento ME, Cintra FA, Sousa Mda L, D'Elboux MJ.


Abstract

CONTEXT AND OBJECTIVE:

Sarcopenia is the main factor involved in the development of frailty syndrome. The aims here were to investigate relationships between lower-limb muscle strength and the variables of sex, age and frailty criteria; compare lower-limb muscle strength with each frailty criterion; and assess the power of each criterion for estimating the risk of frailty among elderly outpatients.

DESIGN AND SETTING:
Cross-sectional study at the Geriatrics Outpatient Clinic of a university hospital in Campinas.

METHOD:
A non-probabilistic convenience sample of 150 elderly people of both sexes who were followed up as outpatients was assessed. Sociodemographic data (sex and age) and physical health data (frailty criteria and the five-times sit-to-stand test) were gathered. Descriptive, comparative and multivariate logistic regression analyses were performed.

RESULTS:
The majority of the elderly people (77.3%) were 70 years of age or over, with predominance of females (64.2%) and had a low score for the five-times sit-to-stand test (81.4% scored 0 or 1); 55.3% of the elderly people presented three or more frailty criteria. A significant association was found between lower-limb muscle strength and the variables of age and number of frailty criteria.

CONCLUSIONS:
Lower levels of lower-limb muscle strength were associated with advanced age and greater presence of signs of frailty. Moreover, lower-limb muscle strength was also associated with the criteria of reduced walking speed criteria and hand-grip strength.

PMID: 22481756

Relationship between lower-limb muscle strength and frailty among elderly people
 
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