The magic of hormones

[madman]

Twice a Week Until Death Do You Part with Dr. Rachel Rubin

Podcast Episode · Circling the Drain · 07/06/2022 · 1h 3m

podcasts.apple.com

Our heads have officially exploded, people. Dr. Rachel Rubin is a board-certified urologist and sexual medicine specialist who dropped so much knowledge and helpful information into one conversation that our puny little brain-sponges got super-soaked. Listen to learn about the two little-known FDA-approved drugs that actually help women's libidos with no negative side effects, why you should be using local vaginal estrogen twice a week for the rest of your life, and how even a doctor can agree with us that the field of medicine is a disgusting dumpster fire of brokenness. As if that weren't enough, we also talk about the Grow Your C**t Movement, Covid Hemorrhoids, and what the hosts never thought they'd do in their 20's that they have done now. Admit it: you're intrigued.

 

[madman]

*why you should be using local vaginal estrogen twice a week for the rest of your life

 

[Nelson Vergel]

I am interviewing her on Tuesday July 19

 

[madman]

I am interviewing her on Tuesday July 19

Looking forward to this Nelson!

 

[tareload]

I am interviewing her on Tuesday July 19

Potential Question 1....

For peri-menopausal/pre-/post- ladies, why the blanket recommendation for vaginal estrogen?

Compare/contrast with labial application of testosterone + / - oral progesterone for these same patients. Based on bloodwork results would this not be a better option especially for the ladies who are in range on E2 but low on T?

 

[tareload]

@Nelson Vergel

Potential question 2...

Based on what we are learning in the TGM population about the adverse cardiovascular effects of supraphysiological T administration for biological females, what your thoughts on the idea of supra T dosing for females in order to provide symptom relief (see example Glaser et al article below)?

Dosing a woman to 300+ ng/dl TT long term? Pellets vs fast acting (1 hr elimination half life) labial T cream? Tradeoff of symptom resolution (major consideration) vs cardiovascular sides (minor?) for the providers who consider these treatments? How do you define objective function for optimization and hard or soft constraints?

More details below.

Does Estrogen Make Me Fat? What about Fertility?

Just watched it. Thanks for sharing. Funny how the presenter talks about the dangers of extrapolation then proceeds at the end to talk about running women to 300 ng/dl mean TT and they feel good. So what’s the problem? Guess we will find out if there is a problem once we have long term data...

forums.t-nation.com

Testosterone implants in women: Pharmacological dosing for a physiologic effect

The objectives of this study were to determine therapeutic serum testosterone (T) levels/ranges and inter-individual variance in women treated with subcutaneous T implants.

www.maturitas.org

 

[Ribeye]

I am interviewing her on Tuesday July 19

I am happy this worked out for the interview. She is a hoot, you will like her. But seriously, a very knowledgable physician who is clearly very dedicated to her patients. She has helped me significantly and I have only been with her a few months.