The Evolution of Testosterone Products in the U.S. (1935-2025)

testosterone products timeline.webp


Thanks to Dr Sun for this diagram.


Timeline details (left → right)
YearProduct (image above/below the line)Form & delivery
1935-1937No product image—text block below the line: “Testosterone first synthesized” with a bullet list of early preparations (oral 17α-methyltestosterone, injectable esterified, 17β-hydroxy testosterone, subdermal pellets).
1979Depo®-Testosterone (vial & carton)intramuscular injection of testosterone cypionate
1995Androderm® (square purple patch package, shown below the line)transdermal patch
2000Androgel® (blue box)transdermal gel
2014Natestonasal gel
2018Xyosted® (auto-injector pen)subcutaneous injection / autoinjector – testosterone enanthate
2019Jatenzo® (white bottle with orange capsules)oral capsules – testosterone undecanoate
March 2022Tlando® (three identical white bottles)oral capsules – testosterone undecanoate
July 2022KYZATREX® (three bottles in differing strengths with tablets scattered)oral capsules – testosterone undecanoate
 
 
 

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