Testosterone Therapy Today: Clinical Advances & Safety with Dr. Abraham Morgentaler

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madman

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Dr. Morgentaler back in action!

Listen closely, loved this one!





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Pros/Cons oral TU (51:24-57:12)

*one of the things that the orals have transformed is the concept that you have to have a continually high level of testosterone to get the benefits and clearly that's not true and the safety profile seems to be improved by having levels that fluctuate some during the day returning to close to or even baseline




Synopsis


Dr. Morgentaler starts by sharing his pioneering journey with testosterone replacement therapy starting in the 1980s, challenging long-held beliefs that it increases prostate cancer risk. He highlights key studies to debunk myths about testosterone’s dangers and emphasizes the ability to improve patients’ quality of life. Further, he discusses modern treatment options and provides practical advice for safely initiating testosterone replacement therapy. Finally, he discusses its use in patients with a history of prostate cancer and emphasizes the importance of individualized treatment plans.


Timestamps

00:00 - Introduction
03:04 - Historical Perspectives on Testosterone and Prostate Cancer
21:31 - Evolution of Testosterone Treatments
31:16 - Testosterone and Prostate Cancer: A Controversial History
35:42 - Treating Prostate Cancer Patients with Testosterone
37:12 - A Case Study
43:05 - Shifting Perspectives
57:15 - Final Thoughts
 
Defy Medical TRT clinic doctor


 
Beyond Testosterone Book by Nelson Vergel
*today we know and I would like to take some credit for it together with my colleague Abdulmaged Traish , we know that there is a limited ability of androgens to stimulate prostate cancer growth or prostate growth and that limit is achieved at a pretty low concentration, we call it the saturation point, prostate tissue needs androgens like testosterone for sure but it can only use a little bit and once you have enough that's it




 
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