Dr. Morgentaler - debunking myths and misconceptions surrounding testosterone

madman

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Dr. Morgentaler, an expert in testosterone therapy, joins the podcast to debunk myths and misconceptions surrounding testosterone. He discusses the importance of testosterone beyond sex, challenges gender bias and stereotypes, and highlights the impact of the Women’s Health Initiative study on testosterone therapy.

Dr. Morgentaler also addresses the reluctance of doctors to advocate for testosterone therapy and the challenges of off-label use and insurance coverage.
He shares exciting developments in testosterone therapy and presents evidence that contradicts the belief that testosterone increases the risk of prostate cancer. He concludes by explaining the paradox of lowering testosterone and its effect on prostate cancer.

The conversation explores the relationship between testosterone and prostate cancer, highlighting the misconception that testosterone drives prostate cancer growth. It is explained that there is a specific range of testosterone levels, around 250 nanograms per deciliter, where prostate growth is optimal. The concept of saturation is introduced, emphasizing that testosterone deprivation is more accurate than testosterone driving cancer.

The discussion then shifts to the idea that different tissues may have different saturation points for testosterone.
The importance of testosterone for quality of life is emphasized, with anecdotes from patients who experienced improved well-being on testosterone replacement therapy. The conversation concludes by addressing the trivialization of hormone deficiency and the need to prioritize quality of life in medical care.




HERE’S WHAT WE DISCUSS

  • Testosterone has important functions beyond sex, including impacts on brain function, muscle and bone health, fat distribution, and red blood cell production.
  • Misconceptions and gender bias have led to skepticism and reluctance among doctors to consider testosterone therapy for various conditions.
  • The Women’s Health Initiative study had a significant impact on the perception of testosterone therapy, leading to a decline in its use.
  • The FDA’s role in regulating testosterone therapy and insurance coverage limitations have created challenges for patients seeking treatment.
  • Recent research, including the Traverse trial, has debunked the myth that testosterone therapy increases the risk of prostate cancer.
 
i am 44yrs now. my psa levels increased from 0.2 to 1 ng/dl in 6months after starting with trt and it has been on 1ng/dl since 6yrs. i check it every 6months, so PSA does increase initial when trt is started
 

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HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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