Testosterone Research Update from Endocrine Society Meeting

Nelson Vergel

Founder, ExcelMale.com
Endocrine Society's 97th Annual Meeting and Expo, March 5–8, 2015 - San Diego

LBF-015: Effect of Testosterone Treatment on Cardiac Biomarkers in a Randomised Controlled Trial of Men with Type 2 Diabetes

Gianatti EJ, Dupuis P, Hoermann R, Strauss BJ, Wentworth JM, Zajac JD, Grossmann M
2014 Effect of testosterone treatment on glucose metabolism in men with type 2 diabetes: a randomized controlled trial. Diabetes Care 37: 2098-2107[


FRI-589: Testosterone Deficiency Is Associated with Greater Deterioration of Glycemic Control during 7-Year Follow up in Men with Type 2 Diabetes

Abstract: Testosterone (T) deficiency in men with type 2 diabetes (T2D) is associated with an
adverse cardiovascular risk profile and increased cardiovascular and all-cause mortality.
Cross-sectional studies have found that low T is associated with insulin resistance and ...[

Increased LH/Testosterone Ratio Is Associated with All-Cause but Not Cardiovascular Disease Mortality; A Long Term Follow-up Study of Danish Men from the …

Abstract: Low testosterone is associated with risk factors for cardiovascular disease (CVD)
and a number of studies have investigated the association between testosterone levels and
subsequent mortality, however with conflicting results. Luteinizing hormone (LH) is the ..

LBF-019: The Importance of Using Plasma Rather Than Serum to Measure Blood TestosteroneLevels in Men Receiving Testosterone Undeconoate for Androgen


Resuming Long-Term Testosterone Replacement Therapy (TRT) on Anthropometric and Metabolic Parameters in Hypogonadal Elderly Men. How Long Should …

Prospective, cumulative, registry study. 262 hypogonadal patients (mean age 59 years) received
testosterone undecanoate (TU) 1000 mg injections in 12-week intervals for a maximum of 11
years. After having been on TRT for a median duration of 5 years, 147 men interrupted .

FRI-132: Effects of Continuous Treatment up to 11 Years with Testosterone Undecanoate Injections (TU) in 115 Hypogonadal Men on Hormonal, Anthropometric and

Methods: Single-center, cumulative, prospective, registry study of 262 hypogonadal men
receiving TU for up to 11 years. Cut-off for total testosterone (T):≤ 12 nmol/L (~ 350 ng/dl). In
147 men, TRT had been temporarily discontinued due to reimbursement issues or ...

SAT-122: A Novel Testosterone Nasal Gel Formulation Normalizes Androgen Levels in Hypogonadal Men

Subjects: among other eligibility criteria, subjects were required to have at least 2 fasting morning
total serum testosterone levels <300 ng/dL. Out of 306 men randomized (n=228 to twice-daily
(BID) and n=78 to three-times-daily (TID) dosing arms) 205 completed the BID arm ...

Serum testosterone levels and symptom-based depression subtypes in men


SAT-130: Men Referred for Borderline Testosterone Levels Have High Rates of Depression

Background: Studies have shown inconsistent results regarding a possible association
between depression and serum testosterone levels. There are few published studies on
adult men who are referred for management of borderline testosterone levels, although ..

SAT-237: High Aromatase Activity in Men with Low Testosterone Is Associated with Higher Spine BMD, Increased Truncal Fat Mass and Reduced Lean Mass

Background: Because the aromatase enzyme catalyzes the conversion of testosterone to
estradiol, the activity of this enzyme could be important in the musculoskeletal health of men
with low testosterone. Objective: To determine the influence of aromatase activity on the .
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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