Testosterone Research Update from Endocrine Society Meeting

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Nelson Vergel

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Beyond Testosterone Book by Nelson Vergel
Endocrine Society's 97th Annual Meeting and Expo, March 5–8, 2015 - San Diego

LBF-015: Effect of Testosterone Treatment on Cardiac Biomarkers in a Randomised Controlled Trial of Men with Type 2 Diabetes

Gianatti EJ, Dupuis P, Hoermann R, Strauss BJ, Wentworth JM, Zajac JD, Grossmann M
2014 Effect of testosterone treatment on glucose metabolism in men with type 2 diabetes: a randomized controlled trial. Diabetes Care 37: 2098-2107[


FRI-589: Testosterone Deficiency Is Associated with Greater Deterioration of Glycemic Control during 7-Year Follow up in Men with Type 2 Diabetes

Abstract: Testosterone (T) deficiency in men with type 2 diabetes (T2D) is associated with an
adverse cardiovascular risk profile and increased cardiovascular and all-cause mortality.
Cross-sectional studies have found that low T is associated with insulin resistance and ...[

Increased LH/Testosterone Ratio Is Associated with All-Cause but Not Cardiovascular Disease Mortality; A Long Term Follow-up Study of Danish Men from the …

Abstract: Low testosterone is associated with risk factors for cardiovascular disease (CVD)
and a number of studies have investigated the association between testosterone levels and
subsequent mortality, however with conflicting results. Luteinizing hormone (LH) is the ..

LBF-019: The Importance of Using Plasma Rather Than Serum to Measure Blood TestosteroneLevels in Men Receiving Testosterone Undeconoate for Androgen


Resuming Long-Term Testosterone Replacement Therapy (TRT) on Anthropometric and Metabolic Parameters in Hypogonadal Elderly Men. How Long Should …

Prospective, cumulative, registry study. 262 hypogonadal patients (mean age 59 years) received
testosterone undecanoate (TU) 1000 mg injections in 12-week intervals for a maximum of 11
years. After having been on TRT for a median duration of 5 years, 147 men interrupted .

FRI-132: Effects of Continuous Treatment up to 11 Years with Testosterone Undecanoate Injections (TU) in 115 Hypogonadal Men on Hormonal, Anthropometric and

Methods: Single-center, cumulative, prospective, registry study of 262 hypogonadal men
receiving TU for up to 11 years. Cut-off for total testosterone (T):≤ 12 nmol/L (~ 350 ng/dl). In
147 men, TRT had been temporarily discontinued due to reimbursement issues or ...

SAT-122: A Novel Testosterone Nasal Gel Formulation Normalizes Androgen Levels in Hypogonadal Men

Subjects: among other eligibility criteria, subjects were required to have at least 2 fasting morning
total serum testosterone levels <300 ng/dL. Out of 306 men randomized (n=228 to twice-daily
(BID) and n=78 to three-times-daily (TID) dosing arms) 205 completed the BID arm ...

Serum testosterone levels and symptom-based depression subtypes in men


SAT-130: Men Referred for Borderline Testosterone Levels Have High Rates of Depression

Background: Studies have shown inconsistent results regarding a possible association
between depression and serum testosterone levels. There are few published studies on
adult men who are referred for management of borderline testosterone levels, although ..

SAT-237: High Aromatase Activity in Men with Low Testosterone Is Associated with Higher Spine BMD, Increased Truncal Fat Mass and Reduced Lean Mass

Background: Because the aromatase enzyme catalyzes the conversion of testosterone to
estradiol, the activity of this enzyme could be important in the musculoskeletal health of men
with low testosterone. Objective: To determine the influence of aromatase activity on the .
 
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