madman
Super Moderator
* Dr. Tombal recommends relugolix, an oral GnRH antagonist that restores normal testosterone within 90 to 120 days, when ADT is required, and notes that patients who fail to recover normal testosterone have worse prognosis.
* He also supports testosterone supplementation in symptomatic hypogonadal patients who have completed ADT and remain in remission.
Bertrand Tombal outlines testosterone recovery dynamics after short-term ADT with radiation therapy. Canadian data show that even a six-month depot LHRH agonist injection leaves 30 to 40% of patients testosterone-suppressed for an extended period. Dr. Tombal recommends relugolix, an oral GnRH antagonist that restores normal testosterone within 90 to 120 days, when ADT is required, and notes that patients who fail to recover normal testosterone have worse prognosis. He also supports testosterone supplementation in symptomatic hypogonadal patients who have completed ADT and remain in remission.
* He also supports testosterone supplementation in symptomatic hypogonadal patients who have completed ADT and remain in remission.
Bertrand Tombal outlines testosterone recovery dynamics after short-term ADT with radiation therapy. Canadian data show that even a six-month depot LHRH agonist injection leaves 30 to 40% of patients testosterone-suppressed for an extended period. Dr. Tombal recommends relugolix, an oral GnRH antagonist that restores normal testosterone within 90 to 120 days, when ADT is required, and notes that patients who fail to recover normal testosterone have worse prognosis. He also supports testosterone supplementation in symptomatic hypogonadal patients who have completed ADT and remain in remission.
