Testosterone Levels Need Not Decline with Age

Jinzang

Member
The Cooper Center measured testosterone levels of men during patient asessment and did a multiple regression to see what factors testosterone levels were associated with they found that testosterone levels were inversely correlated with BMI and correlated with aerobic fitness, but not correlated with age. This suggests the decline in testosterone levels with age can be prevented with healthy lifestyle choices. The summary of the article says:

"In a cross-sectional study of 2994 healthy men aged 50–79 years examined at a preventive medicine clinic from January 2012 to March 2016, screening morning total testosterone levels were measured and categorized as low (<250 ng/dL), low normal (250–399 ng/dL), and normal (>400 ng/dL). Cardiorespiratory fitness (fitness) was estimated from a maximal exercise treadmill test. Multiple logistic regression models were used to test the associations between low testosterone levels and age, body mass index (BMI), and fitness.

"Mean testosterone levels were in the normal range for each age group (50–59, 60–69, and 70–79). There was a similar prevalence of low testosterone in each age group (11·3%, 10%, and 10·5%, respectively). The prevalence of low testosterone was positively associated with BMI and negatively associated with fitness but was not associated with age.

"This study found no evidence that low testosterone is an inevitable consequence of aging. Maintenance of healthy weight and fitness may help maintain normal testosterone levels."
 
The Cooper Center measured testosterone levels of men during patient asessment and did a multiple regression to see what factors testosterone levels were associated with they found that testosterone levels were inversely correlated with BMI and correlated with aerobic fitness, but not correlated with age. This suggests the decline in testosterone levels with age can be prevented with healthy lifestyle choices. The summary of the article says:

"In a cross-sectional study of 2994 healthy men aged 50–79 years examined at a preventive medicine clinic from January 2012 to March 2016, screening morning total testosterone levels were measured and categorized as low (<250 ng/dL), low normal (250–399 ng/dL), and normal (>400 ng/dL). Cardiorespiratory fitness (fitness) was estimated from a maximal exercise treadmill test. Multiple logistic regression models were used to test the associations between low testosterone levels and age, body mass index (BMI), and fitness.

"Mean testosterone levels were in the normal range for each age group (50–59, 60–69, and 70–79). There was a similar prevalence of low testosterone in each age group (11·3%, 10%, and 10·5%, respectively). The prevalence of low testosterone was positively associated with BMI and negatively associated with fitness but was not associated with age.

"This study found no evidence that low testosterone is an inevitable consequence of aging. Maintenance of healthy weight and fitness may help maintain normal testosterone levels."

Too bad the summary leaves out key metrics.

Such as the percentage of men in the low normal range. For me, that is the most important range.

And they seem to want to make a conclusion that weight and fitness causes low testosterone, while I would suggest low testosterone is what causes weight gain and low fitness.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
2
Guests online
496
Total visitors
498

Latest posts

Back
Top