I am having a issue. I recently started with defy again. As my doc retired. I was doing 20mg eod this kept my T at 500-600 with free T middle of the road. E2 was around 25 on quest ultra sensitive. On defy I got moved to 28mg eod. This gives me a level of 700-800 and free T upper range on multiple tests. E2 was 28. My SHBG was 31. My issues are libido is gone , penis seems cold and tight. Erections are slightly worse also. Can the extra T do that? Can one be sensitive to androgens? I also get almost a anxiety feel as well. I don’t see E2 as being the issue.