Testosterone, Estrogen & Menopause: Dr. Kelly Casperson Unpacks FDA Women’s Health Breakthroughs + The Future of HRT & Mental Health

madman

Super Moderator

In this episode of You Are Not Broken, Dr. Kelly Casperson recaps the recent FDA event dedicated to women’s health, spotlighting the critical role of hormones like testosterone and estrogen. She shares key insights from expert panels, explains why better education and prescribing practices are urgently needed among physicians, and reveals exciting details about her upcoming book on menopause. Kelly also explores the mental health impact of hormonal changes during perimenopause and offers a preview of her nationwide book tour aimed at rewriting the conversation around midlife health.




Chapters


00:00 Introduction and Podcast Growth
02:24 Insights from the FDA Event
05:21 The Need for Female Dose Testosterone
08:19 Diversity in Hormone Discussions
10:49 The Importance of Hormones in Aging
13:17 Book Launch and Pre-Order Details
16:21 Upcoming Book Tour
18:44 Hormones and Mental Health
21:45 Preventative Use of Hormones
24:13 Animal Hormone Replacement Therapy
27:09 Conclusion and Call to Action
 
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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