Navigating Menopause: Expert Insights and Solutions

madman

Super Moderator

In Episode #245, I'm joined by endocrinologist and clinical researcher Professor Susan Davis, AO. In this detailed exchange – taking place over more than two hours – Professor Davis shares the best practice guidelines for managing menopause.

You will learn from a world-leading expert about sex hormones, the physiological changes underpinning menopause, signs, and symptoms of peri-menopause/menopause, the struggles of menopause, medical and lifestyle interventions for managing menopause (including hormone therapy), testosterone and sexual desire, the beautiful side of menopause, and plenty more.

Professor Susan R Davis AO is Director, of Monash University Women’s Health Research Program and an NHMRC Senior Research Fellow; Consultant Endocrinologist and Head, of Women’s Endocrine Clinic, Alfred Hospital Melbourne; and consultant at Cabrini Medical Centre.

Her research spans from basic science to clinical trials and has been pivotal in the understanding of sex hormones in women across the lifespan in multiple non-reproductive target tissues, including the brain (cognition, mood, sexual function), cardiovascular system (lipids, vascular function, and coagulation), and other tissues (fat, muscle, joint cartilage, and bone).


Specifically, we cover:

00:00 Intro
06:00 Understanding Menopause: Communication and Misconceptions
10:48 Hysterectomy and its Impact on Menopause
15:48 Medical Consultation during Menopause: Is it necessary?
18:03 In-Depth Discussion on Menopause Symptoms and Phases
28:28 Menopause as a Part of the Aging Process
30:47 Hormones and Reproduction during Menopause
33:10 Women's Experiences and Body Changes during Menopause
48:20 Estrogen and Sex Hormones during Menopause
59:10 A Proactive Approach to Menopause: Starting Early for Symptom Management
1:04:31 Guidelines for Managing Menopause
1:13:28 Hormone Replacement Therapy (HRT)
1:24:30 HRT and Breast Cancer Risk
1:26:50 HRT Medications: Guidelines and Recommendations
1:45:35 The Trustworthiness of Big Pharmaceutical Corporations
1:55:12 Breast Cancer and Menopause Medications
1:58:00 The Funding of Menopause Research
2:00:10 Testosterone Therapy in Menopausal Hormone Treatment
2:18:55 Empowering Menopausal Women: Their Continued Contributions to Society
2:19:40 Outro
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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