Testosterone Dosage Change Effects

GreenMachineX

Well-Known Member
Basic question, how long from changing from let’s say 120mg testosterone per week to 100mg testosterone per week would you notice the effects, such as lowered libido, and more importantly, when would you see the resulting drop in hematocrit?
 
For most members to drop their HCT levels, you need longevity with trt. It took two years before I got my HCT under control. I haven't needed to donate blood for almost 2 years.
For me to feel a difference in my protocol, it takes 12 weeks. Personally I feel I need more than 6 weeks to steady My levels.
 
For most members to drop their HCT levels, you need longevity with trt. It took two years before I got my HCT under control. I haven't needed to donate blood for almost 2 years.
For me to feel a difference in my protocol, it takes 12 weeks. Personally I feel I need more than 6 weeks to steady My levels.
That’s exactly what I was hoping to hear. I know now no matter what I can’t use more than 100mg per week, but I think using telmisartan this lower dosage my hct might be stable around 50. I’m going to retest every couple weeks.
 
The last time I tried going to 80mg a week, I’m pretty sure it crashed my e2. My e2 sensitive runs at 17 at 100mg per week, so I can’t go lower.
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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