Testosterone and Platelet Count

Smokin Joe

Active Member
Just wanted to share an observation while being on Testosterone.
I have Immune Thrombocytopenia where my system eats up a % of my platelets regularly. Hematologist doesn't know why just happens.
I've noticed that when I'm on T my platelet count goes up to around 120 to 130 every time.

Currently off of T platelets have dropped to 108 - 112. Had them checked twice recently due to back procedures.
Gives me the impression that Testosterone is pro platelets?
Any comments welcome.
S.J.
 
I have not noticed. Testosterone affecting my platelet count. I do keep an eye on it because it does normally run on the lower end. My doctor tells me it's nothing to worry about until it gets down into the '90s. Mine had never got below the lowest end of range.
 
My data suggest this:
[IMG='width:340px; width="340px"']https://i.ibb.co/jvYsVhn/Screen-Shot-2022-10-26-at-11-25-18-AM.png[/IMG]

Only real bump I've gotten is with 50 mg oxandrolone daily for 4 weeks. Did a replicate. Obviously lipids not worth the platelet effect in my particular case.

For some reason Cataceous can post pics but I can't. Jealous.

Tried using the insert image function as well as just copying into the post window. No luck.
 
Cataceous,
I would tend to agree as using 100 mg weekly is when I get the best bump up.
As soon as I get this prostate biopsy I'll make up my mind about moving forward.
It's funny though as I get older how my system has changed as far as tolerating certain things.
I have been using low dose pregnenolone for three weeks and it's working fine as a standalone.
Used to be I couldn't take it at all.
But DHEA at any doze is a no go.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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