madman
Super Moderator
Abstract
Hypogonadism in men results from the failure of the testes to produce physiological levels of testosterone and a normal number of spermatozoa due to a disruption of the hypothalamic-pituitary-testicular axis. An example of secondary hypogonadism as a result of anabolic steroid abuse is presented with the case report of a man who committed suicide after a history of aggressive behavior and physical abuse of his wife. The autopsy revealed shrunken testicles, with more than 30% of parenchymatous sclerosis, absent spermatogenesis, and very few Leydig cells detected only by immunohistochemistry. A low-specific immunochemical analysis revealed a very high level of total testosterone (serum 109.8 nmol/L; urine 81.2 nmol/L). A more accurate analysis confirmed an overdose of synthetic anabolic steroids. Doctors in different medical areas should be alerted to chronic abusers of synthetic anabolic steroids among the growing number of recreational athletes.
Conclusion
The spread of a sports culture, that uses a variety of tools and substances, to the growing number of recreational athletes, also has drawbacks, because among them there are those who try to achieve their goals at any cost. Because they are uninformed about the harmful effects of the selected shortcut, such as taking synthetic anabolic steroids, these users suffer from temporary or permanent psychosomatic changes, often seeking help; initially from general practitioners, but later from urologists, internists, psychiatrists or others who should be alerted to the negative side of a “healthy sporting life”.
Hypogonadism in men results from the failure of the testes to produce physiological levels of testosterone and a normal number of spermatozoa due to a disruption of the hypothalamic-pituitary-testicular axis. An example of secondary hypogonadism as a result of anabolic steroid abuse is presented with the case report of a man who committed suicide after a history of aggressive behavior and physical abuse of his wife. The autopsy revealed shrunken testicles, with more than 30% of parenchymatous sclerosis, absent spermatogenesis, and very few Leydig cells detected only by immunohistochemistry. A low-specific immunochemical analysis revealed a very high level of total testosterone (serum 109.8 nmol/L; urine 81.2 nmol/L). A more accurate analysis confirmed an overdose of synthetic anabolic steroids. Doctors in different medical areas should be alerted to chronic abusers of synthetic anabolic steroids among the growing number of recreational athletes.
Conclusion
The spread of a sports culture, that uses a variety of tools and substances, to the growing number of recreational athletes, also has drawbacks, because among them there are those who try to achieve their goals at any cost. Because they are uninformed about the harmful effects of the selected shortcut, such as taking synthetic anabolic steroids, these users suffer from temporary or permanent psychosomatic changes, often seeking help; initially from general practitioners, but later from urologists, internists, psychiatrists or others who should be alerted to the negative side of a “healthy sporting life”.
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