In 1999, 1 year after the approval of the first oral phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction(ED), the first Princeton Consensus Conference was held to address the clinical management of men with ED who also had cardiovascular disease. These issues were readdressed in the second and third conferences. In the 13 years since the last Princeton Consensus Conference, the experience with PDE5 inhibitors is more robust, and recent new data have emerged regarding not only...
Independent Risk Marker: Erectile dysfunction (ED) should be considered an independent risk marker for coronary artery disease (CAD). It predates significant cardiac events, including myocardial infarctions and sudden cardiac deaths, often by several years. Thus, it can serve as an early indicator for potential cardiovascular issues.
Inclusion in Risk Calculators: The P4 panel advocates for the inclusion of ED as a risk-enhancing factor in cardiovascular risk assessment tools. Currently, only the QRISK calculator incorporates...